Trabecular meshwork movement controls distal valves and Chambers: new glaucoma medical and surgical targets
M Johnstone, C Xin, E Martin, R Wang - Journal of Clinical Medicine, 2023 - mdpi.com
Herein, we provide evidence that human regulation of aqueous outflow is by a pump-conduit
system similar to that of the lymphatics. Direct observation documents pulsatile aqueous flow …
system similar to that of the lymphatics. Direct observation documents pulsatile aqueous flow …
Real-time line-field optical coherence tomography for cellular resolution imaging of biological tissue
A real-time line-field optical coherence tomography (LF-OCT) system is demonstrated with
image acquisition rates of up to 5000 B-frames or 2.5 million A-lines per second for 500 A …
image acquisition rates of up to 5000 B-frames or 2.5 million A-lines per second for 500 A …
Dynamic traction force in trabecular meshwork cells: A 2D culture model for normal and glaucomatous states
Glaucoma, which is associated with intraocular pressure (IOP) elevation, results in
trabecular meshwork (TM) cellular dysfunction, leading to increased rigidity of the …
trabecular meshwork (TM) cellular dysfunction, leading to increased rigidity of the …
Implementing new computational methods for the study of JCT and SC inner wall basement membrane biomechanics and hydrodynamics
Purpose The conventional aqueous outflow pathway, which includes the trabecular
meshwork (TM), juxtacanalicular tissue (JCT), and the inner wall endothelium of Schlemm's …
meshwork (TM), juxtacanalicular tissue (JCT), and the inner wall endothelium of Schlemm's …
Segmental biomechanics of the normal and glaucomatous human aqueous outflow pathway
The conventional aqueous outflow pathway, encompassing the trabecular meshwork (TM),
juxtacanalicular connective tissue (JCT), and inner wall endothelium of Schlemm's canal …
juxtacanalicular connective tissue (JCT), and inner wall endothelium of Schlemm's canal …
Biomechanics of the JCT and SC inner wall endothelial cells with their basement membrane using 3D serial block-face scanning electron microscopy
Background: More than~ 70% of the aqueous humor exits the eye through the conventional
aqueous outflow pathway that is comprised of the trabecular meshwork (TM) …
aqueous outflow pathway that is comprised of the trabecular meshwork (TM) …
Comparative analysis of traction forces in normal and glaucomatous trabecular meshwork cells within a 3D, active fluid-structure interaction culture environment
This study presents a 3D in vitro cell culture model, meticulously 3D printed to replicate the
conventional aqueous outflow pathway anatomical structure, facilitating the study of …
conventional aqueous outflow pathway anatomical structure, facilitating the study of …
High-resolution modeling of aqueous humor dynamics in the conventional outflow pathway of a normal human donor eye
Background and objective The conventional aqueous outflow pathway, which includes the
trabecular meshwork (TM), juxtacanalicular tissue (JCT), and inner wall endothelium of …
trabecular meshwork (TM), juxtacanalicular tissue (JCT), and inner wall endothelium of …
[HTML][HTML] Consensus Recommendations for Studies of Outflow Facility and Intraocular Pressure Regulation Using Ex Vivo Perfusion Approaches
Intraocular pressure (IOP) elevation is the primary risk factor and currently the main treatable
factor for progression of glaucomatous optic neuropathy. In addition to direct clinical and …
factor for progression of glaucomatous optic neuropathy. In addition to direct clinical and …