Protein disulfide isomerase is regulated in multiple ways: Consequences for conformation, activities, and pathophysiological functions
L Wang, J Yu, C Wang - Bioessays, 2021 - Wiley Online Library
Protein disulfide isomerase (PDI) is one of the most abundant and critical protein folding
catalysts in the endoplasmic reticulum of eukaryotic cells. PDI consists of four thioredoxin …
catalysts in the endoplasmic reticulum of eukaryotic cells. PDI consists of four thioredoxin …
Biophysical and in-silico studies on the structure-function relationship of Brugia malayi protein disulfide isomerase
Human Lymphatic filariasis is caused by parasitic nematodes Wuchereria bancrofti, Brugia
malayi, and Brugia timori. Protein disulfide isomerase (PDI), a redox-active enzyme, helps to …
malayi, and Brugia timori. Protein disulfide isomerase (PDI), a redox-active enzyme, helps to …
Conserved Arg451 residue is critical for maintaining the stability and activity of thioredoxin glutathione reductase
Thioredoxin glutathione reductase (TGR), a potential anthelminthic drug target causes
NADPH-dependent transfer of electrons to both thioredoxins and glutathione systems. In the …
NADPH-dependent transfer of electrons to both thioredoxins and glutathione systems. In the …
Simple fluorescent reagents for monitoring disulfide reductase and S-nitroso reductase activities in vitro and in live cells in culture
N Onukwue, L Ventimiglia, M Potter, S Aljoudi, B Mutus - Methods, 2019 - Elsevier
This study describes the theoretical basis and the methods for the facile synthesis and
characterization of four fluorogenic probes, N-amido-O-aminobenzoyl-S-nitrosoglutathione …
characterization of four fluorogenic probes, N-amido-O-aminobenzoyl-S-nitrosoglutathione …
[图书][B] Roles of Extracellular Vesicle-Borne Protein Disulfide Isomerase in Bladder Cancer Recurrence
CH Wu - 2022 - search.proquest.com
The high recurrence rate of non-muscle-invasive bladder cancer (NMIBC) poses significant
clinical and financial burdens. NMIBC is often multi-chronotropic and multifocal, and the …
clinical and financial burdens. NMIBC is often multi-chronotropic and multifocal, and the …
Structure-function relationship in S-nitrosoglutathione reductase and the development of fluorogenic pseudo-substrates
NC Onukwue - 2019 - search.proquest.com
S-nitrosation is the attachment of a nitric oxide moiety to the thiol side chain of cysteine. S-
nitrosoglutathione (GSNO) acts as a bioactive reservoir for NO to maintain an equilibrium in …
nitrosoglutathione (GSNO) acts as a bioactive reservoir for NO to maintain an equilibrium in …