Heterogeneity‐induced NGF‐NGFR communication inefficiency promotes mitotic spindle disorganization in exhausted T cells through PREX1 suppression to impair …
X Wang, T Yang, S Shi, C Xu, F Wang, D Dai… - Cancer …, 2024 - Wiley Online Library
Background The mechanism of decreased T cells infiltrating tumor tissues in hepatocellular
carcinoma is poorly understood. Methods Cells were separated from the single‐cell RNA …
carcinoma is poorly understood. Methods Cells were separated from the single‐cell RNA …
The role of immunophenotyping in common variable immunodeficiency: a narrative review
J Neirinck, M Buysse, C De Vriendt… - Critical Reviews in …, 2024 - Taylor & Francis
Common variable immunodeficiency (CVID) is a heterogeneous primary immunodeficiency
(PID) characterized by an impaired immunoglobulin production, in association with an …
(PID) characterized by an impaired immunoglobulin production, in association with an …
Impaired B cell recall memory and reduced antibody avidity but robust T cell response in CVID patients after COVID-19 vaccination
S Steiner, T Schwarz, VM Corman… - Journal of Clinical …, 2023 - Springer
Purpose Humoral and cellular immune responses were described after COVID-19
vaccination in patients with common variable immunodeficiency disorder (CVID). This study …
vaccination in patients with common variable immunodeficiency disorder (CVID). This study …
STAT expression and TFH1 cells in CVID granulomatosis and sarcoidosis: immunological and histopathological comparisons
JF Viallard, M Lescure, E Oksenhendler, P Blanco… - Virchows Archiv, 2024 - Springer
Granulomatous disease is a serious complication of common variable immunodeficiency
(CVID-GD) that occurs in 8–22% of these patients and can mimic sarcoidosis, with which it …
(CVID-GD) that occurs in 8–22% of these patients and can mimic sarcoidosis, with which it …
The dysfunction of Tfh cells promotes pediatric recurrent respiratory tract infections development by interfering humoral immune responses
J Diao, H Liu, H Cao, W Chen - Heliyon, 2023 - cell.com
Recurrent respiratory tract infections (RRTIs) are one of the most common pediatric
diseases. Although the pathogenesis of pediatric RRTIs remains unknown, ineffective B cell …
diseases. Although the pathogenesis of pediatric RRTIs remains unknown, ineffective B cell …
Natural history of type 1 diabetes on an immunodysregulatory background with genetic alteration in B-cell activating factor receptor: A case report
B Di Lorenzo, L Pacillo, G Milardi, T Jofra… - Frontiers in …, 2022 - frontiersin.org
The immunological events leading to type 1 diabetes (T1D) are complex and
heterogeneous, underscoring the necessity to study rare cases to improve our …
heterogeneous, underscoring the necessity to study rare cases to improve our …
[HTML][HTML] In-depth immune profiling reveals advanced B-and T-cell differentiation to be associated with Th1-driven immune dysregulation in common variable …
J Hultberg, E Blixt, R Göransson, J Adolfsson… - Clinical …, 2023 - Elsevier
Common variable immunodeficiency (CVID) is an inborn error of immunity characterized by
low levels of antibodies. In addition to infections, many patients also suffer from T-helper 1 …
low levels of antibodies. In addition to infections, many patients also suffer from T-helper 1 …
ICOS agonist vopratelimab modulates follicular helper T cells and improves B cell function in common variable immunodeficiency
Common variable immunodeficiency (CVID) is an immune defect characterized by
hypogammaglobulinemia and impaired development of B cells into plasma cells. As …
hypogammaglobulinemia and impaired development of B cells into plasma cells. As …
Emergence of a senescent and inflammatory pulmonary CD4+ T cell population prior to lung allograft failure
S Moshkelgosha, L Levy, S Safavi, S Karunagaran… - bioRxiv, 2023 - biorxiv.org
Lung transplantation is a life-saving therapy for end-stage pulmonary disease, but its long-
term outlook is poor due to a high incidence of chronic lung allograft dysfunction (CLAD) …
term outlook is poor due to a high incidence of chronic lung allograft dysfunction (CLAD) …
成人普通变异型免疫缺陷病1 例报道并文献复习
钟海媚， 凌华湘， 黄立霞， 王红燕 - 中华全科医学, 2024 - zhqkyx.net
本文报道1 例成人普通变异型免疫缺陷病(CVID), 患者男性, 38 岁, 发病前身体素质良好, 10
年前开始因反复发生肺部及其他部位感染多次住院, 此次因“肺部感染” 再次入院 …
年前开始因反复发生肺部及其他部位感染多次住院, 此次因“肺部感染” 再次入院 …