Carbohydrate-based macromolecular biomaterials

L Su, Y Feng, K Wei, X Xu, R Liu, G Chen - Chemical Reviews, 2021 - ACS Publications
Carbohydrates are the most abundant and one of the most important biomacromolecules in
Nature. Except for energy-related compounds, carbohydrates can be roughly divided into …

Viral nanoparticles for drug delivery, imaging, immunotherapy, and theranostic applications

YH Chung, H Cai, NF Steinmetz - Advanced Drug Delivery Reviews, 2020 - Elsevier
Viral nanoparticles (VNPs) encompass a diverse array of naturally occurring nanomaterials
derived from plant viruses, bacteriophages, and mammalian viruses. The application and …

Design of virus-based nanomaterials for medicine, biotechnology, and energy

AM Wen, NF Steinmetz - Chemical Society Reviews, 2016 - pubs.rsc.org
This review provides an overview of recent developments in “chemical virology.” Viruses, as
materials, provide unique nanoscale scaffolds that have relevance in chemical biology and …

Protein-based nanoparticles in cancer vaccine development

M Neek, TI Kim, SW Wang - Nanomedicine: Nanotechnology, Biology and …, 2019 - Elsevier
Peptide and protein-based cancer vaccines usually fail to elicit efficient immune responses
against tumors. However, delivery of these peptides and proteins as components within …

Virus-based nanoparticles as versatile nanomachines

KJ Koudelka, AS Pitek, M Manchester… - Annual review of …, 2015 - annualreviews.org
Nanoscale engineering is revolutionizing the way we prevent, detect, and treat diseases.
Viruses have played a special role in these developments because they can function as …

[HTML][HTML] Immunomodulatory glycomedicine: Introducing next generation cancer glycovaccines

R Freitas, A Peixoto, E Ferreira, A Miranda… - Biotechnology …, 2023 - Elsevier
Cancer remains a leading cause of death worldwide due to the lack of safer and more
effective therapies. Cancer vaccines developed from neoantigens are an emerging strategy …

Application of plant viruses in biotechnology, medicine, and human health

S Venkataraman, K Hefferon - Viruses, 2021 - mdpi.com
Plant-based nanotechnology programs using virus-like particles (VLPs) and virus
nanoparticles (VNPs) are emerging platforms that are increasingly used for a variety of …

Inter-coat protein loading of active ingredients into Tobacco mild green mosaic virus through partial dissociation and reassembly of the virion

I González-Gamboa, AA Caparco, J McCaskill… - Scientific Reports, 2024 - nature.com
Chemical pesticide delivery is a fundamental aspect of agriculture. However, the extensive
use of pesticides severely endangers the ecosystem because they accumulate on crops, in …

The plant viruses and molecular farming: how beneficial they might be for human and animal health?

G Zahmanova, AA Aljabali, K Takova, V Toneva… - International Journal of …, 2023 - mdpi.com
Plant viruses have traditionally been studied as pathogens in the context of understanding
the molecular and cellular mechanisms of a particular disease affecting crops. In recent …

A vision for vaccines built from fully synthetic tumor-associated antigens: from the laboratory to the clinic

RM Wilson, SJ Danishefsky - Journal of the American Chemical …, 2013 - ACS Publications
Cancer cells may be distinguished from normal cells by cell surface displays of aberrant
levels and types of carbohydrate domains. Accordingly, these tumor-associated …