Spermatogenesis is completely dependent on the pituitary hormone follicle-stimulating
hormone (FSH) and androgens locally produced in response to luteinising hormone (LH) …

Human spermatogonia are target for exploration of adult stem cell characteristics and
potential source for the development of therapeutic applications. Almost 50 years ago, Yves …

Genome editing is a powerful new tool for making precise alterations to an organism's
genetic material. Recent scientific advances have made genome editing more efficient …

BACKGROUND Childhood cancer incidence and survivorship are both on the rise.
However, many lifesaving treatments threaten the prepubertal testis. Cryopreservation of …

During the past decade, advances in cancer treatment have increased survival rates of both
boys and men. However, cancer treatment itself can compromise fertility, especially …

Cryopreservation is a useful approach to preserve male fertility for assisted reproduction
technique and other evaluations. In spite of extensive development in the cryopreservation …

Medical treatments for cancers or other conditions can lead to permanent infertility. Infertility
is an insidious disease that impacts not only the ability to have a biological child but also the …

Stem cell therapy and exosome therapy are the two experimental methods that are now at
the center of attention. Various types of stem cells, especially mesenchymal stem cells and …

Improved therapies for cancer and other conditions have resulted in a growing population of
long-term survivors. Infertility is an unfortunate side effect of some cancer therapies that …

BACKGROUND Although the prognosis of childhood cancer survivors has increased
dramatically during recent years, chemotherapy and radiation treatments for cancer and …