Abdominal aortic aneurysm (AAA) is a lethal degenerative vascular disease that affects,
mostly, the elder population, with a high mortality rate (> 80%) upon rupture. It features a …

Necroptosis, a cell death modality that is defined as a necrosis-like cell death depending on
the receptor-interacting protein kinase 3 (RIPK3) and mixed lineage kinase domain-like …

In the last 10 years, mortality from acute myocardial infarction (AMI) has not significantly
decreased. This situation is associated with the absence in clinical practice of highly …

Necroptosis, which is distinct from apoptosis and necrosis, serves a crucial role in ontogeny
and the maintenance of homeostasis. In the last decade, it has been demonstrated that the …

Extensive research work has been carried out to define the exact significance and
contribution of regulated necrosis-like cell death program, such as necroptosis to cardiac …

Objectives Abdominal aortic aneurysm (AAA) is a cardiovascular disease with high mortality
and pathogenesis closely related to various cell death types, eg, autophagy, apoptosis and …

Necroptosis, a form of programmed lytic cell death, has emerged as a driving factor in the
pathogenesis of acute lung injury (ALI). As ALI is often associated with a cytokine storm, we …

Background Myocardial fibrosis (MF) remains a prominent challenge in heart disease. The
role of receptor-interacting protein kinase 3 (RIPK3)-mediated necroptosis is evident in the …

Myocardial infarction and revascularization cause cardiac ischemia/reperfusion (I/R) injury
featuring cardiomyocyte death and inflammation. The Ca 2+/calmodulin dependent protein …

Aortic aneurysm is a potentially deadly disease. It is chronic degeneration of the aortic wall
that involves an inflammatory response and the immune system, aberrant remodeling of the …