Glioma targeted therapy: insight into future of molecular approaches

K Yang, Z Wu, H Zhang, N Zhang, W Wu, Z Wang… - Molecular Cancer, 2022 - Springer
Gliomas are the common type of brain tumors originating from glial cells. Epidemiologically,
gliomas occur among all ages, more often seen in adults, which males are more susceptible …

Pediatric low-grade glioma in the era of molecular diagnostics

S Ryall, U Tabori, C Hawkins - Acta neuropathologica communications, 2020 - Springer
Low grade gliomas are the most frequent brain tumors in children and encompass a
spectrum of histologic entities which are currently assigned World Health Organisation …

Role of artificial intelligence in radiogenomics for cancers in the era of precision medicine

S Saxena, B Jena, N Gupta, S Das, D Sarmah… - Cancers, 2022 - mdpi.com
Simple Summary Recently, radiogenomics has played a significant role and offered a new
understanding of cancer's biology and behavior in response to standard therapy. It also …

Adrenocortical carcinoma

T Else, AC Kim, A Sabolch, VM Raymond… - Endocrine …, 2014 - academic.oup.com
Adrenocortical carcinoma (ACC) is a rare endocrine malignancy, often with an unfavorable
prognosis. Here we summarize the knowledge about diagnosis, epidemiology …

UK guidelines for the management of soft tissue sarcomas

A Dangoor, B Seddon, C Gerrand, R Grimer… - Clinical sarcoma …, 2016 - Springer
Soft tissue sarcomas (STS) are rare tumours arising in mesenchymal tissues, and can occur
almost anywhere in the body. Their rarity, and the heterogeneity of subtype and location …

Comparison of cancer prevalence in patients with neurofibromatosis type 1 at an academic cancer center vs in the general population from 1985 to 2020

JP Landry, KL Schertz, YJ Chiang, AD Bhalla… - JAMA Network …, 2021 - jamanetwork.com
Importance Neurofibromatosis type 1 (NF1) is a complex genetic disorder that is associated
with not only neurofibromas, but also an increased susceptibility to other neoplasms …

Ras in cancer and developmental diseases

A Fernández-Medarde, E Santos - Genes & cancer, 2011 - journals.sagepub.com
Somatic, gain-of-function mutations in ras genes were the first specific genetic alterations
identified in human cancer about 3 decades ago. Studies during the last quarter century …

Intersection of diverse neuronal genomes and neuropsychiatric disease: The Brain Somatic Mosaicism Network

MJ McConnell, JV Moran, A Abyzov, S Akbarian, T Bae… - Science, 2017 - science.org
BACKGROUND Elucidating the genetic architecture of neuropsychiatric disorders remains a
major scientific and medical challenge. Emerging genomic technologies now permit the …

Guidelines for the management of soft tissue sarcomas

R Grimer, I Judson, D Peake, B Seddon - Sarcoma, 2010 - Wiley Online Library
These guidelines were drawn up following a consensus meeting of UK sarcoma specialists
convened under the auspices of the British Sarcoma Group and are intended to provide a …

Genotype-phenotype correlation in NF1: evidence for a more severe phenotype associated with missense mutations affecting NF1 codons 844–848

M Koczkowska, Y Chen, T Callens, A Gomes… - The American Journal of …, 2018 - cell.com
Neurofibromatosis type 1 (NF1), a common genetic disorder with a birth incidence of 1:
2,000–3,000, is characterized by a highly variable clinical presentation. To date, only two …