K Saeki, G Chang, N Kanaya, X Wu, J Wang… - Communications …, 2021 - nature.com
The female mammary epithelium undergoes reorganization during development, pregnancy, and menopause, linking higher risk with breast cancer development. To …
Oriented cell divisions are critical for the formation and maintenance of structured epithelia. Proper mitotic spindle orientation relies on polarised anchoring of force generators to the …
F Citron, I Segatto, GLR Vinciguerra, L Musco, F Russo… - Cancer research, 2020 - AACR
Abstract miR-223 is an anti-inflammatory miRNA that in cancer acts either as an oncosuppressor or oncopromoter, in a context-dependent manner. In breast cancer, we …
M Falconi, M Giangrossi, ME Zabaleta… - The FASEB …, 2019 - Wiley Online Library
tRNA‐derived fragments (tRFs) have been defined as a novel class of small noncoding RNAs. tRFs have been reported to be deregulated in cancer, but their biologic function …
I Pellarin, A Dall'Acqua, A Gambelli, I Pellizzari… - Oncogene, 2020 - nature.com
In epithelial ovarian cancer (EOC), response to platinum (PT)-based chemotherapy dictates subsequent treatments and predicts patients' prognosis. Alternative splicing is often …
Simple Summary The high incidence and death rates of breast cancer make the development of new therapies an urgent need. The introduction into the clinic of the anti …
F Citron, I Segatto, L Musco, I Pellarin… - EMBO Molecular …, 2021 - embopress.org
Radiotherapy (RT) plus the anti‐EGFR monoclonal antibody Cetuximab (CTX) is an effective combination therapy for a subset of head and neck squamous cell carcinoma (HNSCC) …
C Askeland, E Wik, K Finne, E Birkeland, JB Arnes… - Scientific reports, 2020 - nature.com
Studies indicate that stathmin expression associates with PI3K activation in breast cancer, suggesting stathmin as a marker for targetable patient subgroups. Here we assessed …
I Pellarin, B Belletti… - Medicinal research reviews, 2021 - Wiley Online Library
Since its discovery, alternative splicing has been recognized as a powerful way for a cell to amplify the genetic information and for a living organism to adapt, evolve, and survive. We …