Classic psychedelic drugs such as psilocybin and lysergic acid diethylamide (LSD) have
recaptured the imagination of both science and popular culture, and may have efficacy in …

Abstract Serotonergic hallucinogens, such as (+)-lysergic acid diethylamide, psilocybin, and
mescaline, are somewhat enigmatic substances. Although these drugs are derived from …

Hallucinogens fall into several different classes, as broadly defined by pharmacological
mechanism of action, and chemical structure. These include psychedelics, entactogens …

Kappa-opioid receptors (KOR) are widely expressed throughout the central nervous system,
where they modulate a range of physiological processes depending on their location …

Salvia is one of the largest genera of the family Lamiaceae. It is widely distributed in the
temperate, subtropical, and tropical regions all over the world. Besides its ethnobotanical …

Medicinal use of Cannabis sativa L. has an extensive history and it was essential in the
discovery of phytocannabinoids, including the Cannabis major psychoactive compound—Δ9 …

Schizophrenia is a complex mental health disorder with positive, negative and cognitive
symptom domains. Approximately one third of patients are resistant to currently available …

In this paper, we present the development of the Altered States Database (ASDB), an open-
science project based on a systematic literature review. The ASDB contains psychometric …

Kappa opioid receptors and their endogenous neuropeptide ligand, dynorphin A, are
densely localized in limbic and cortical areas comprising the brain reward system, and …

The regulation of new psychoactive substances (NPS) has confounded governments
throughout the western world. In 2014 the UK government convened an NPS Review Expert …