Stem cells: their source, potency and use in regenerative therapies with focus on adipose-derived stem cells–a review

L Bacakova, J Zarubova, M Travnickova… - Biotechnology …, 2018 - Elsevier
Stem cells can be defined as units of biological organization that are responsible for the
development and the regeneration of organ and tissue systems. They are able to renew their …

Adipose stem cells: biology and clinical applications for tissue repair and regeneration

LE Kokai, K Marra, JP Rubin - Translational Research, 2014 - Elsevier
There is a clear clinical need for cell therapies to repair or regenerate tissue lost to disease
or trauma. Adipose tissue is a renewable source of stem cells, called adipose-derived stem …

Safety and clinical effects of mesenchymal stem cells secreting neurotrophic factor transplantation in patients with amyotrophic lateral sclerosis: results of phase 1/2 …

P Petrou, Y Gothelf, Z Argov, M Gotkine, YS Levy… - JAMA …, 2016 - jamanetwork.com
Importance Preclinical studies have shown that neurotrophic growth factors (NTFs) extend
the survival of motor neurons in amyotrophic lateral sclerosis (ALS) and that the combined …

ALS pathogenesis and therapeutic approaches: the role of mesenchymal stem cells and extracellular vesicles

R Bonafede, R Mariotti - Frontiers in cellular neuroscience, 2017 - frontiersin.org
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by
progressive muscle paralysis determined by the degeneration of motoneurons in the motor …

Current strategies to enhance adipose stem cell function: an update

Y Seo, TH Shin, HS Kim - International journal of molecular sciences, 2019 - mdpi.com
Mesenchymal stem cells (MSCs) emerged as a promising therapeutic tool targeting a variety
of inflammatory disorders due to their multiple remarkable properties, such as superior …

Mesenchymal stromal cell therapies for neurodegenerative diseases

NP Staff, DT Jones, W Singer - Mayo Clinic Proceedings, 2019 - Elsevier
Mesenchymal stromal cells are multipotent cells that are being used to treat a variety of
medical conditions. Over the past decade, there has been considerable excitement about …

Mesenchymal stromal cells and their secretome: new therapeutic perspectives for skeletal muscle regeneration

M Sandonà, L Di Pietro, F Esposito… - … in bioengineering and …, 2021 - frontiersin.org
Mesenchymal stromal cells (MSCs) are multipotent cells found in different tissues: bone
marrow, peripheral blood, adipose tissues, skeletal muscle, perinatal tissues, and dental …

Mesenchymal stem cell-derived exosomes from different sources selectively promote neuritic outgrowth

MA Lopez-Verrilli, A Caviedes, A Cabrera, S Sandoval… - Neuroscience, 2016 - Elsevier
Mesenchymal stem cells (MSCs) obtained from bone marrow (BM) have been shown to
promote neuronal growth and survival. However, the comparative effects of MSCs of …

Functional role of mesenchymal stem cells in the treatment of chronic neurodegenerative diseases

D Lo Furno, G Mannino… - Journal of cellular …, 2018 - Wiley Online Library
Mesenchymal stem cells (MSCs) can differentiate into not only cells of mesodermal
lineages, but also into endodermal and ectodermal derived elements, including neurons …

Adipose tissue stem cells for therapy: an update on the progress of isolation, culture, storage, and clinical application

DT Chu, T Nguyen Thi Phuong, NLB Tien… - Journal of Clinical …, 2019 - mdpi.com
Adipose tissue stem cells (ASCs), known as multipotent stem cells, are most commonly used
in the clinical applications in recent years. Adipose tissues (AT) have the advantage in the …