Glycosylation of viral proteins: Implication in virus–host interaction and virulence
T Feng, J Zhang, Z Chen, W Pan, Z Chen, Y Yan, J Dai - Virulence, 2022 - Taylor & Francis
Glycans are among the most important cell molecular components. However, given their
structural diversity, their functions have not been fully explored. Glycosylation is a vital post …
structural diversity, their functions have not been fully explored. Glycosylation is a vital post …
ER stress, the unfolded protein response and osteoclastogenesis: a review
W Huang, Y Gong, L Yan - Biomolecules, 2023 - mdpi.com
Endoplasmic reticulum (ER) stress and its adaptive mechanism, the unfolded protein
response (UPR), are triggered by the accumulation of unfolded and misfolded proteins …
response (UPR), are triggered by the accumulation of unfolded and misfolded proteins …
Signal peptide and N-glycosylation of N-terminal-CD2v determine the hemadsorption of African swine fever virus
D Pérez-Núñez, R García-Belmonte, E Riera… - Journal of …, 2023 - Am Soc Microbiol
African swine fever virus (ASFV) is the cause of African swine fever (ASF), a devastating
disease that affects domestic pigs and wild boar and is currently responsible for the largest …
disease that affects domestic pigs and wild boar and is currently responsible for the largest …
A metabolic modeling approach reveals promising therapeutic targets and antiviral drugs to combat COVID-19
F Santos-Beneit, V Raškevičius, VA Skeberdis… - Scientific reports, 2021 - nature.com
In this study we have developed a method based on Flux Balance Analysis to identify
human metabolic enzymes which can be targeted for therapeutic intervention against …
human metabolic enzymes which can be targeted for therapeutic intervention against …
Unheeded SARS-CoV-2 proteins? A deep look into negative-sense RNA
M Bartas, A Volná, CA Beaudoin… - Briefings in …, 2022 - academic.oup.com
SARS-CoV-2 is a novel positive-sense single-stranded RNA virus from the Coronaviridae
family (genus Betacoronavirus), which has been established as causing the COVID-19 …
family (genus Betacoronavirus), which has been established as causing the COVID-19 …
SARS-CoV-2 activates ER stress and Unfolded protein response
ABSTRACT Coronavirus disease-2019 (COVID-19) pandemic caused by the SARS-CoV-2
coronavirus infection is a major global public health concern affecting millions of people …
coronavirus infection is a major global public health concern affecting millions of people …
Exploring the potential of chemical inhibitors for targeting post-translational glycosylation of coronavirus (SARS-CoV-2)
The Spike (S) protein of SARS-CoV-2 expressed on the viral cell surface is of particular
importance as it facilitates viral entry into the host cells. The S protein is heavily glycosylated …
importance as it facilitates viral entry into the host cells. The S protein is heavily glycosylated …
Compatibility of the Ligand Binding Sites in the Spike Glycoprotein of COVID-19 with those in the Aminopeptidase and the Caveolins 1, 2 Proteins
AA Dawood, MA Altobje… - Research Journal of …, 2021 - indianjournals.com
A novel severe viral pneumonia emerged in Wuhan city, China, in December 2019. The
spike glycoprotein of the SARS-CoV-2 plays a crucial role in the viral entry to the host cell …
spike glycoprotein of the SARS-CoV-2 plays a crucial role in the viral entry to the host cell …
Proteomic identification of intracellular vesicle trafficking and protein glycosylation requirements for lumen inflation in Ciona notochord
Z Wang, Z Tan, J Bi, A Liu, A Jiang, B Dong - Proteomics, 2023 - Wiley Online Library
Lumen formation and inflation are crucial steps for tubular organ morphogenesis, yet the
underling mechanism remains largely unrevealed. Here, we applied 4D proteomics to …
underling mechanism remains largely unrevealed. Here, we applied 4D proteomics to …
VT68. 2: an antibody to chondroitin sulfate proteoglycan 4 (CSPG4) displays reactivity against a tumor-associated carbohydrate antigen
B Nounamo, F Jousheghany, ER Siegel… - International Journal of …, 2023 - mdpi.com
The anti-CSPG4 monoclonal antibodies (mAbs) have shown anti-tumor activity and
therapeutic potential for treating breast cancer. In addition, CSPG4 is a dominant tumor …
therapeutic potential for treating breast cancer. In addition, CSPG4 is a dominant tumor …