The presence of extracellular circulating or cell-free RNA in biological fluids is becoming a
promising diagnostic tool for non invasive and cost effective cancer detection. Extracellular …

The deficiencies of serum PSA as a prostate-cancer-specific diagnostic test are well
recognized. Thus, the development of novel biomarkers for prostate cancer detection …

Background The highly intra-tumoral heterogeneity and complex cell origination of prostate
cancer greatly limits the utility of traditional bulk RNA sequencing in finding better biomarker …

The study of the human urinary proteome has the potential to offer significant insights into
normal physiology as well as disease pathology. The information obtained from such studies …

Purpose We studied the ethnicity-specific expression of prostate cancer (PC)–associated
biomarkers to evaluate whether genetic/biologic factors affect ethnic disparities in PC …

Hepatocellular carcinomas (HCCs) and bile duct carcinomas (BDCs) have a poor prognosis.
Therefore, surveillance strategies including sensitive and specific serum markers for early …

Multiple, complex molecular events characterize cancer development and progression.
Deciphering the molecular networks that distinguish organ-confined disease from metastatic …

Background Prostate cancer is the most common cancer in American men that ranges from
low risk states amenable to active surveillance to high-risk states that can be lethal …

Our recent study of microRNA (miRNA) expression signature of prostate cancer (PCa) has
revealed that the microRNA-143/145 (miR-143/145) cluster is significantly downregulated in …

Background & Aims Levels of the Golgi protein 73 (GP73) increase during development of
hepatocellular carcinoma (HCC); GP73 is a serum marker for HCC. However, little is known …