PURPOSE To provide guidance on the use of opioids to manage pain from cancer or cancer
treatment in adults. METHODS A systematic review of the literature identified systematic …

We conducted an analytic review of the clinical scientific literature bearing on the use of
opioids for treatment of chronic non-cancer pain. There is substantial, albeit not definitive …

This guideline provides recommendations for clinicians providing pain care, including those
prescribing opioids, for outpatients aged≥ 18 years. It updates the CDC Guideline for …

Importance Opioid-related mortality and national prescribing guidelines have led to tapering
of doses among patients prescribed long-term opioid therapy for chronic pain. There is …

Description: In May 2022, leadership within the US Department of Veterans Affairs (VA) and
US Department of Defense (DoD) approved a joint clinical practice guideline for the use of …

Importance Opioid dosage tapering has emerged as a strategy to reduce harms associated
with long-term opioid therapy; however, evidence supporting this approach is limited …

Importance Rapid reduction or discontinuation of long-term opioid therapy may increase risk
of opioid overdose or opioid use disorder (OUD). Current guidelines for chronic pain …

Importance Patients prescribed long-term opioid therapy are increasingly undergoing dose
tapering. Recent studies suggest that tapering is associated with short-term risks of …

From April 2020 through April 2021, 75,673 Americans died from opioid overdoses, nearly
one-quarter of which directly involved prescription opioids. 1 This represents the first time …

Pain is a common symptom accompanying the coronavirus disease 2019 (COVID-19)
caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). Nonspecific …