Adrenocortical carcinoma (ACC) is a highly malignant infrequent tumor with a dismal
prognosis. microRNAs (miRNAs, miRs) are crucial in post-transcriptional gene expression …

Radiotherapy (RT) remains one of the current main treatment strategies for many types of
cancer. However, how to improve RT efficiency while reducing its side effects is still a large …

A novel nontoxic denatured bovine serum albumin (dBSA)-based platform for effectively
delivering drugs was prepared. It was demonstrated that the as-prepared dBSA micelles …

In this study, we performed the characterization and synthesis of biocompatible and targeted
albumin and graphene oxide (GO) dual-carrier paclitaxel (PTX) nanoparticles for …

Adrenocortical carcinoma (ACC) is a heterogeneous malignancy related to poor prognosis
and limited treatment options. The orphan drug mitotane (MT) is still a cornerstone in ACC …

Definition of the molecular pathogenesis of lung cancer allows investigators an enhanced
understanding of the natural history of the disease, thus fostering development of new …

Purpose The primary objective of this study was to evaluate the dose-limiting toxicities
(DLTs) and identify the maximum-tolerated dose (MTD) and recommended dose of nab …

The clinical efficacy of cytotoxic drugs in the treatment of cancer is often hampered by poor
pharmacodynamics and systemic toxicity. Here, we describe the design and synthesis of a …

Plant natural products are a plethora of diverse and complex molecules produced by the
plant secondary metabolism. Among these, many can reserve beneficial or curative …

Adrenocortical carcinomas (ACCs) are rare, heterogeneous and very malignant endocrine
tumors with a poor prognosis. An important prerequisite to optimize existing therapeutic …