The interaction of coagulation factors with the perivascular environment affects the
development of disease in ways that extend beyond their traditional roles in the acute …

Obesity is a major risk factor for type 2 diabetes mellitus (T2DM), which is a significant health
problem worldwide. Active disease is associated with low-grade chronic inflammation …

Low‐grade inflammation, a minor elevation in the baseline concentration of inflammatory
markers such as C‐reactive protein (CRP), is nowadays recognized as an important …

Cardiovascular diseases (CVDs) are a leading cause of global morbidity and mortality,
significantly driven by chronic inflammation. Interleukin-6 (IL-6) and interleukin-1β (IL-1β) …

Atherosclerotic arterial occlusive disease affecting the lower extremities is also known as
peripheral artery disease (PAD). This disorder affects 8 to 12 million individuals in the US …

Background Systemic biomarkers provide insights into disease pathogenesis, diagnosis,
and risk stratification. Many systemic biomarker concentrations are heritable phenotypes …

Abstract The IL-6− 174G/C (rs1800795), TNF-α− 308G/A (rs1800629) and− 238 G/A
(rs361525) and SDF-1 801 G/A (rs1801157) are well characterized SNPs which have …

Peripheral arterial disease (PAD) is a manifestation of atherosclerotic vascular disease and
is often associated with other comorbidities, such as hypertension, diabetes and …

Diabetes mellitus is a combined metabolic disorder which includes hyperglycemia,
dyslipidemia, stroke and several other complications. Various groups all over the world are …

Psoriasis is a common cutaneous disorder characterized by abnormal epidermal
differentiation, proliferation and inflammation mediated by dermal infiltrates, such as T cells …