Extracellular vesicles from human umbilical cord mesenchymal stem cells facilitate diabetic wound healing through MiR-17-5p-mediated enhancement of …

Q Wei, Y Wang, K Ma, Q Li, B Li, W Hu, X Fu… - Stem cell reviews and …, 2022 - Springer
Endothelial dysfunction caused by persistent hyperglycemia in diabetes is responsible for
impaired angiogenesis in diabetic wounds. Extracellular vehicles (EVs) are considered …

Ultra-sensitive detection by metal nanoparticles-mediated enhanced SPR biosensors

F Fathi, MR Rashidi, Y Omidi - Talanta, 2019 - Elsevier
Surface plasmon resonance (SPR), as an optical technique, has widely been used for the
detection of biomarkers. Various investigations have been conducted to address the impacts …

Quercetin alleviates high glucose-induced damage on human umbilical vein endothelial cells by promoting autophagy

A Rezabakhsh, R Rahbarghazi, H Malekinejad, F Fathi… - Phytomedicine, 2019 - Elsevier
Background Quercetin, a flavonoid antioxidant, has been found to exert therapeutic effects in
diabetic condition. Autophagy represents a homeostatic cellular mechanism for the turnover …

mTOR signalling pathway in stem cell bioactivities and angiogenesis potential

H Lotfimehr, N Mardi, S Narimani… - Cell …, 2023 - Wiley Online Library
The mammalian target of rapamycin (mTOR) is a protein kinase that responds to different
stimuli such as stresses, starvation and hypoxic conditions. The modulation of this effector …

Rapamycin inhibits oxidative/nitrosative stress and enhances angiogenesis in high glucose-treated human umbilical vein endothelial cells: role of autophagy

A Rezabakhsh, M Ahmadi, M Khaksar… - Biomedicine & …, 2017 - Elsevier
Chronic hyperglycemia is a potent risk factor of abnormal angiogenesis with various tissue
diseases. Autophagy, as an alternative cell response, is mostly generated by a vast array of …

Alginate‐gelatin encapsulation of human endothelial cells promoted angiogenesis in in vivo and in vitro milieu

S Nemati, A Rezabakhsh… - Biotechnology and …, 2017 - Wiley Online Library
Up to present, many advantages have been achieved in the field of cell‐based therapies by
applying sophisticated methodologies and delivery approaches. Microcapsules are capable …

Effect of melatonin on exosomal dynamics in bovine cumulus cells

M Pournaghi, R Khodavirdilou, MAE Saadatlou… - Process …, 2021 - Elsevier
In this study, the effects of melatonin were investigated on the exosome release from bovine
cumulus cells after 7 days. Cells were randomly allocated into three groups as follows; …

Metformin improves the senescence of renal tubular epithelial cells in a high-glucose state through E2F1

D Liang, Z Li, Z Feng, Z Yuan, Y Dai, X Wu… - Frontiers in …, 2022 - frontiersin.org
Diabetic kidney disease is a major cause of chronic kidney condition and the most common
complication of diabetes. The cellular senescence participates in the process of diabetic …

Early-stage detection of VE-cadherin during endothelial differentiation of human mesenchymal stem cells using SPR biosensor

F Fathi, A Rezabakhsh, R Rahbarghazi… - Biosensors and …, 2017 - Elsevier
Surface plasmon resonance (SPR) biosensors are most commonly applied for real-time
dynamic analysis and measurement of interactions in bio-molecular studies and cell …

Taohong Siwu Decoction Promotes Osteo‐Angiogenesis in Fractures by Regulating the HIF‐1α Signaling Pathway

Z Tang, M Yin, Y Guo, W Li, F Sun… - Evidence‐Based …, 2022 - Wiley Online Library
Background. Vascular damage is a major consequence of bone fracture. Taohong Siwu
decoction (TSD) can raise the expression of vascular endothelial growth factor (VEGF) in …