[HTML][HTML] The expanding incretin universe: from basic biology to clinical translation

DJ Drucker, JJ Holst - Diabetologia, 2023 - Springer
Incretin hormones, principally glucose-dependent insulinotropic polypeptide (GIP) and
glucagon-like peptide-1 (GLP-1), potentiate meal-stimulated insulin secretion through direct …

Incretin hormones: Their role in health and disease

MA Nauck, JJ Meier - Diabetes, Obesity and Metabolism, 2018 - Wiley Online Library
Incretin hormones are gut peptides that are secreted after nutrient intake and stimulate
insulin secretion together with hyperglycaemia. GIP (glucose‐dependent insulinotropic …

The intestine as an endocrine organ and the role of gut hormones in metabolic regulation

R Bany Bakar, F Reimann, FM Gribble - … reviews Gastroenterology & …, 2023 - nature.com
Gut hormones orchestrate pivotal physiological processes in multiple metabolically active
tissues, including the pancreas, liver, adipose tissue, gut and central nervous system …

Ghrelin, CCK, GLP-1, and PYY (3–36): secretory controls and physiological roles in eating and glycemia in health, obesity, and after RYGB

RE Steinert, C Feinle-Bisset, L Asarian… - Physiological …, 2017 - journals.physiology.org
The efficacy of Roux-en-Y gastric-bypass (RYGB) and other bariatric surgeries in the
management of obesity and type 2 diabetes mellitus and novel developments in …

[HTML][HTML] Regulation of postabsorptive and postprandial glucose metabolism by insulin-dependent and insulin-independent mechanisms: an integrative approach

GD Dimitriadis, E Maratou, A Kountouri, M Board… - Nutrients, 2021 - mdpi.com
Glucose levels in blood must be constantly maintained within a tight physiological range to
sustain anabolism. Insulin regulates glucose homeostasis via its effects on glucose …

The incretin effect in healthy individuals and those with type 2 diabetes: physiology, pathophysiology, and response to therapeutic interventions

MA Nauck, JJ Meier - The lancet Diabetes & endocrinology, 2016 - thelancet.com
The incretin effect describes the phenomenon whereby oral glucose elicits higher insulin
secretory responses than does intravenous glucose, despite inducing similar levels of …

Inflammation, defective insulin signaling, and mitochondrial dysfunction as common molecular denominators connecting type 2 diabetes to Alzheimer disease

FG De Felice, ST Ferreira - Diabetes, 2014 - Am Diabetes Assoc
A growing body of evidence supports an intriguing clinical/epidemiological connection
between Alzheimer disease (AD) and type 2 diabetes (T2D). T2D patients have significantly …

[HTML][HTML] The role of catechins in regulating diabetes: an update review

L Wen, D Wu, X Tan, M Zhong, J Xing, W Li, D Li, F Cao - Nutrients, 2022 - mdpi.com
Catechins are key functional components in tea and have many health benefits, including
relieving diabetes. Glucose is necessary for maintaining life. However, when the glucose in …

A concise review of non-alcoholic fatty liver disease

NN Than, PN Newsome - Atherosclerosis, 2015 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) is the hepatic manifestation of the metabolic
syndrome and the incidence of which is rising rapidly due to the increasing epidemic of …

[HTML][HTML] The incretin system in healthy humans: the role of GIP and GLP-1

JJ Holst - Metabolism, 2019 - Elsevier
The incretin effect, the amplification of insulin secretion occurring when glucose is taken in
orally as compared to infused intravenously, is one of the factors that help the body to …