The promise of precision medicine in rheumatology

JM Guthridge, CA Wagner, JA James - Nature medicine, 2022 - nature.com
Systemic autoimmune rheumatic diseases (SARDs) exhibit extensive heterogeneity in
clinical presentation, disease course, and treatment response. Therefore, precision …

[PDF][PDF] Pathogenesis of rheumatoid arthritis: one year in review 2022

F Petrelli, FM Mariani, A Alunno… - Clin Exp …, 2022 - clinexprheumatol.org
The mechanisms underlying the pathogenesis of rheumatoid arthritis (RA) involve different
components of the immune system. In subjects with genetic predisposition to develop RA, a …

Lupus nephritis risk factors and biomarkers: An update

Y Renaudineau, W Brooks, J Belliere - International Journal of Molecular …, 2023 - mdpi.com
Lupus nephritis (LN) represents the most severe organ manifestation of systemic lupus
erythematosus (SLE) in terms of morbidity and mortality. To reduce these risks, tremendous …

[HTML][HTML] SARS-Cov2 acute and post-active infection in the context of autoimmune and chronic inflammatory diseases

R Larionova, K Byvaltsev, О Kravtsova, E Takha… - Journal of Translational …, 2022 - Elsevier
The clinical and immunological spectrum of acute and post-active COVID-19 syndrome
overlaps with criteria used to characterize autoimmune diseases such as rheumatoid …

[HTML][HTML] New insights into the taxonomy of autoimmune diseases based on polyautoimmunity

M Rojas, C Ramírez-Santana, Y Acosta-Ampudia… - Journal of …, 2022 - Elsevier
Objective The clinical coexistence of two or more autoimmune diseases (ADs) fulfilling
classification criteria is termed “overt polyautoimmunity”(PolyA), whereas the presence of …

Acupuncture improves immunity and fatigue after chemotherapy in breast cancer patients by inhibiting the Leptin/AMPK signaling pathway

J Li, R Fu, X Guo, Z Pan, J Xie - Supportive Care in Cancer, 2023 - Springer
Objective Acupuncture has become a popular complementary treatment in oncology. This
study is based on RNA-Seq transcriptome sequencing technology to investigate the …

ImmUniverse Consortium: Multi-omics integrative approach in personalized medicine for immune-mediated inflammatory diseases

S Vetrano, G Bouma, RJ Benschop… - Frontiers in …, 2022 - frontiersin.org
Immune mediated inflammatory diseases (IMIDs) are a heterogeneous group of debilitating,
multifactorial and unrelated conditions featured by a dysregulated immune response leading …

The role of b cells in scleroderma lung disease pathogenesis

SNC Liossis, C Staveri - Frontiers in Medicine, 2022 - frontiersin.org
Systemic sclerosis (SSc) is a chronic, autoimmune, multisystem disease characterized by
tissue fibrosis that, apart from the skin, may affect the lungs among other organs. B cells …

Characteristics of the (auto) reactive T cells in rheumatoid arthritis according to the immune epitope database

C Carlé, Y Degboe, A Ruyssen-Witrand… - International Journal of …, 2023 - mdpi.com
T cells are known to be involved in the pathogenesis of rheumatoid arthritis (RA).
Accordingly, and to better understand T cells' contribution to RA, a comprehensive review …

HAMP as a prognostic biomarker for colorectal cancer based on tumor microenvironment analysis

FZ Wei, SW Mei, ZJ Wang, JN Chen, FQ Zhao… - Frontiers in …, 2022 - frontiersin.org
Colorectal cancer (CRC) is the most common digestive tumor in the world and has a high
mortality rate. The development and treatment of CRC are related to the immune …