Macrophages exposed to inflammatory stimuli including LPS undergo metabolic
reprogramming to facilitate macrophage effector function. This metabolic reprogramming …

Amino acids are basic nutrients for immune cells during organ development, tissue
homeostasis, and the immune response. Regarding metabolic reprogramming in the tumor …

Amino acids are fundamental building blocks supporting life. Their role in protein synthesis
is well defined, but they contribute to a host of other intracellular metabolic pathways …

Macrophages act as scavengers, modulating the immune response against pathogens and
maintaining tissue homeostasis. Metabolism governs macrophage differentiation …

Metabolic rewiring and epigenetic remodeling, which are closely linked and reciprocally
regulate each other, are among the well-known cancer hallmarks. Recent evidence …

Metabolites produced by the host and microbiota play a crucial role in how human bodies
develop and remain healthy. Most of these metabolites are produced by microbiota and …

Immune cell function and metabolism are closely linked. Many studies have now clearly
demonstrated that alterations in cellular metabolism influence immune cell function and that …

Metabolism in immune cells is no longer thought of as merely a process for adenosine
triphosphate (ATP) production, biosynthesis, and catabolism. The reprogramming of …

Following detection of bacteria, macrophages switch their metabolism from oxidative
respiration through the tricarboxylic acid cycle to high-rate aerobic glycolysis. This …

Branched chain amino acids (BCAAs), leucine, isoleucine and valine, are essential amino
acids widely studied for their crucial role in the regulation of protein synthesis mainly through …