Ovarian cancer has poor survival rates due to a combination of diagnosis at advanced
disease stages and disease recurrence as a result of platinum chemotherapy resistance …

Despite advances in therapy, ovarian cancer remains the most deadly of the gynecological
cancers. Less than 30% of women with advanced stage disease survive long‐term. When …

Many forms of cancer have multiple subtypes with different causes and clinical outcomes.
Somatic tumor genome sequences provide a rich new source of data for uncovering these …

Accumulating evidence suggests that mesenchymal stem cells (MSCs) are recruited to the
tumor microenvironment; however, controversy exists regarding their role in solid tumors. In …

Although bone morphogenetic proteins (BMPs) initially showed effective induction of ectopic
bone growth in muscle, it has since been determined that these proteins, as members of the …

Bone morphogenetic proteins (BMPs) act as central regulators of ovarian physiology and
may be involved in ovarian cancer development. In an effort to understand these processes …

Whether human cancer follows a hierarchical or stochastic model of differentiation is
controversial. Furthermore, the factors that regulate cancer stem-like cell (CSC) …

Study Design. Literature review. Objective. To evaluate the association between
recombinant human bone morphogenetic protein-2 (rhBMP-2) and malignancy. Summary of …

Bone morphogenetic proteins (BMPs) were first studied as growth factors or morphogens of
the transforming growth factor-beta superfamily. These growth molecules, originally …

BACKGROUND: Bone morphogenetic protein (BMP) is used in tens of thousands of spinal
fusions each year. A trial evaluating a high-dose BMP formulation demonstrated that its use …