Pathogenesis of autoimmune disease
DS Pisetsky - Nature Reviews Nephrology, 2023 - nature.com
Autoimmune diseases are a diverse group of conditions characterized by aberrant B cell
and T cell reactivity to normal constituents of the host. These diseases occur widely and …
and T cell reactivity to normal constituents of the host. These diseases occur widely and …
Gut barrier disruption and chronic disease
The intestinal barrier protects the host against gut microbes, food antigens, and toxins
present in the gastrointestinal tract. However, gut barrier integrity can be affected by intrinsic …
present in the gastrointestinal tract. However, gut barrier integrity can be affected by intrinsic …
Gut microbiota from green tea polyphenol-dosed mice improves intestinal epithelial homeostasis and ameliorates experimental colitis
Z Wu, S Huang, T Li, N Li, D Han, B Zhang, ZZ Xu… - Microbiome, 2021 - Springer
Background Alteration of the gut microbiota may contribute to the development of
inflammatory bowel disease (IBD). Epigallocatechin-3-gallate (EGCG), a major bioactive …
inflammatory bowel disease (IBD). Epigallocatechin-3-gallate (EGCG), a major bioactive …
Oral microbiota in human systematic diseases
Oral bacteria directly affect the disease status of dental caries and periodontal diseases. The
dynamic oral microbiota cooperates with the host to reflect the information and status of …
dynamic oral microbiota cooperates with the host to reflect the information and status of …
Gut microbiota in COVID-19: key microbial changes, potential mechanisms and clinical applications
The gastrointestinal tract is involved in coronavirus disease 2019 (COVID-19) caused by
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The gut microbiota has …
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The gut microbiota has …
Epithelial barrier hypothesis: effect of the external exposome on the microbiome and epithelial barriers in allergic disease
Environmental exposure plays a major role in the development of allergic diseases. The
exposome can be classified into internal (eg, aging, hormones, and metabolic processes) …
exposome can be classified into internal (eg, aging, hormones, and metabolic processes) …
Intestinal barrier in human health and disease
N Di Tommaso, A Gasbarrini, FR Ponziani - International journal of …, 2021 - mdpi.com
The intestinal mucosa provides a selective permeable barrier for nutrient absorption and
protection from external factors. It consists of epithelial cells, immune cells and their …
protection from external factors. It consists of epithelial cells, immune cells and their …
The immunology of systemic lupus erythematosus
GC Tsokos - Nature Immunology, 2024 - nature.com
Understanding the pathogenesis and clinical manifestations of systemic lupus
erythematosus (SLE) has been a great challenge. Reductionist approaches to understand …
erythematosus (SLE) has been a great challenge. Reductionist approaches to understand …
Gut microbiome, liver immunology, and liver diseases
R Wang, R Tang, B Li, X Ma, B Schnabl… - Cellular & molecular …, 2021 - nature.com
The gut microbiota is a complex and plastic consortium of microorganisms that are intricately
connected with human physiology. The liver is a central immunological organ that is …
connected with human physiology. The liver is a central immunological organ that is …
Combined effects of host genetics and diet on human gut microbiota and incident disease in a single population cohort
Human genetic variation affects the gut microbiota through a complex combination of
environmental and host factors. Here we characterize genetic variations associated with …
environmental and host factors. Here we characterize genetic variations associated with …