Icariin is a biologically active substance in Epimedii herba that is used for the treatment of
neurologic disorders. However, a comprehensive analysis of the molecular mechanisms of …

Multiple sclerosis (MS) is a chronic autoimmune disease of the central nervous system
(CNS) characterized by focal inflammatory lesions and prominent demyelination. Even …

Multiple sclerosis is a chronic autoimmune disease of the central nervous system and is
generally considered to be a non-traumatic, physically debilitating neurological disorder. In …

Exercise is increasingly recommended as a supportive therapy for people with Multiple
Sclerosis (pwMS). While clinical research has still not disclosed the real benefits of exercise …

Multiple sclerosis (MS) is an inflammatory, demyelinating disease with an unknown origin.
Previous studies showed the involvement of the hypothalamic–pituitary–adrenal (HPA) axis …

Multiple sclerosis (MS) is associated with burdensome memory impairments and preclinical
literature suggests that these impairments are linked to neuroinflammation. Previously, we …

Multiple sclerosis (MS) is an inflammatory demyelinating neurodegenerative disease that
negatively affects neurotransmission. It can be pathologically mimicked by experimental …

Methamphetamine (METH) use disorder has been shown to be in high comorbidity with
cognitive deficits. METH-induced cognitive deficits are accompanied by neurotoxicity which …

Thimet oligopeptidase (THOP1) is thought to be involved in neuropeptide metabolism,
antigen presentation, neurodegeneration, and cancer. Herein, the generation of THOP1 …

Highlights•Glucocorticoid receptors (GRs) control brain cell functions at the neurovascular
unit.•Glucocorticoid receptor dysfunction is associated with neuropathological conditions.• …