Zebrafish are teleosts (bony fish) that share with mammals a common ancestor belonging to
the phylum Osteichthyes, from which their endoskeletal systems have been inherited …

Tissue damage can resolve completely through healing and regeneration, or can produce
permanent scarring and loss of function. The response to tissue damage varies across …

Regeneration is a complex chain of events that restores a tissue to its original size and
shape. The tissue-wide coordination of cellular dynamics that is needed for proper …

Animal models are essential tools for addressing fundamental scientific questions about
skeletal diseases and for the development of new therapeutic approaches. Traditionally …

Attaining proper organ size during development and regeneration hinges on the activity of
mitogenic factors. Here, we performed a large-scale chemical screen in embryonic zebrafish …

Danio rerio (zebrafish) is an elective model organism for the study of vertebrate
development because of its high degree of homology with human genes and organs …

Background Scales are mineralised exoskeletal structures that are part of the dermal
skeleton. Scales have been mostly lost during evolution of terrestrial vertebrates whilst bony …

Danionella cerebrum is a new vertebrate model that offers an exciting opportunity to
visualize dynamic biological processes in intact adult animals. Key advantages of this model …

Zebrafish (Danio rerio) are aquatic vertebrates with significant homology to their terrestrial
counterparts. While zebrafish have a centuries-long track record in developmental and …

Rare monogenic disorders often exhibit significant phenotypic variability among individuals
sharing identical genetic mutations. Bruck syndrome (BS), a prime example, is characterized …