Cancer is one of the leading causes of morbidity and mortality worldwide. Traditional
treatments include surgery, chemotherapy and radiation therapy, and more recently targeted …

Breast cancer is the most common malignancy in the female population with a high mortality
rate. Despite the satisfying depth of studies evaluating the contributory role of immune …

Tumor immune escape is associated with both, the expression of immune checkpoint
molecules on peripheral immune cells and soluble forms of the human leukocyte antigen-G …

Immunotherapy for cancer is making impressive strides at improving survival of a subset of
cancer patients. To increase the breadth of patients that benefit from immunotherapy, new …

Breast cancer progression and metastasis are governed by a complex interplay within the
tumor immune microenvironment (TIME), involving numerous cell types. Lymph node …

Backgrounds In recent years, many studies have shown that insulin resistance is related to
the occurrence of thyroid cancer, but there are few reports on whether the two are related …

The tumor immune microenvironment (TIME) plays a pivotal role in tumor development,
progression, and prognosis. However, the characteristics of the TIME in diffuse astrocytoma …

Background We aimed to develop a time‐resolved fluorescence immunoassay (TRFIA) for
detecting soluble T‐cell immunoglobulin and mucin domain 3 (sTim3) in serum samples and …

Cancer treatment through immune checkpoint receptor blockade has made significant
advances in the recent years. However, resistance to the current immune checkpoint …

Objectives: PD1/PDL1 pathway targeting using antibodies shows immune related adverse
events in patients with tumors. The masking of PD1 ligand by soluble human PD-1 (shPD-1) …