Quantitative high-throughput profiling of snake venom gland transcriptomes and proteomes (Ovophis okinavensis and Protobothrops flavoviridis)

SD Aird, Y Watanabe, A Villar-Briones, MC Roy… - BMC genomics, 2013 - Springer
Background Advances in DNA sequencing and proteomics have facilitated quantitative
comparisons of snake venom composition. Most studies have employed one approach or …

Venom of several Indian green pit vipers: Comparison of biochemical activities and cross-reactivity with antivenoms

S Thakur, A Malhotra, S Giri, HT Lalremsanga… - Toxicon, 2022 - Elsevier
Green pit vipers, a name that can refer to several unrelated species, comprise a large group
of venomous snakes found across the humid areas of tropical and sub-tropical Asia, and are …

Mechanistic Insights into the Anti-angiogenic Activity of Trypanosoma cruzi Protein 21 and its Potential Impact on the Onset of Chagasic Cardiomyopathy

SC Teixeira, DS Lopes, SNC Gimenes, TL Teixeira… - Scientific reports, 2017 - nature.com
Chronic chagasic cardiomyopathy (CCC) is arguably the most important form of the Chagas
Disease, caused by the intracellular protozoan Trypanosoma cruzi; it is estimated that 10 …

Delineating the venom toxin arsenal of Malabar pit viper (Trimeresurus malabaricus) from the Western Ghats of India and evaluating its immunological cross-reactivity …

M Vanuopadath, SK Shaji, D Raveendran… - International journal of …, 2020 - Elsevier
The venom protein components of Malabar pit viper (Trimeresurus malabaricus) were
identified by combining SDS-PAGE and ion-exchange chromatography pre-fractionation …

Inhibitory potential of three zinc chelating agents against the proteolytic, hemorrhagic, and myotoxic activities of Echis carinatus venom

ANN Urs, M Yariswamy, C Ramakrishnan, V Joshi… - Toxicon, 2015 - Elsevier
Viperbites undeniably cause local manifestations such as hemorrhage and myotoxicity
involving substantial degradation of extracellular matrix (ECM) at the site of envenomation …

Elucidation of procoagulant mechanism and pathophysiological significance of a new prothrombin activating metalloprotease purified from Daboia russelii russelii …

R Thakur, P Chattopadhyay, SS Ghosh, AK Mukherjee - Toxicon, 2015 - Elsevier
The procoagulant proteases present in Russell's Viper venom (RVV) are responsible for
promoting consumption coagulopathy in victims. In this study, a procoagulant …

Toxins from venomous animals: gene cloning, protein expression and biotechnological applications

MF Fernandes-Pedrosa, J Félix-Silva… - An Integrated View of …, 2013 - books.google.com
Venoms are the secretion of venomous animals, which are synthesized and stored in
specific areas of their body ie, venom glands. The animals use venoms for defense and/or to …

Characterization of major zinc containing myonecrotic and procoagulant metalloprotease 'malabarin'from non lethal Trimeresurus malabaricus snake venom with …

CD Raghavendra Gowda… - Current topics in …, 2011 - ingentaconnect.com
A major myonecrotic zinc containing metalloprotease 'malabarin'with thrombin like activity
was purified by the combination of gel permeation and anion exchange chromatography …

Biochemical and functional characterization of Bothropoidin: the first haemorrhagic metalloproteinase from Bothrops pauloensis snake venom

MSR Gomes, DL Naves de Souza… - The journal of …, 2015 - academic.oup.com
We present the biochemical and functional characterization of Bothropoidin, the first
haemorrhagic metalloproteinase isolated from Bothrops pauloensis snake venom. This …

Flaxseed cysteine protease exhibits strong anticoagulant, antiplatelet, and clot-dissolving properties

SKM Nandish, J Kengaiah, C Ramachandraiah… - Biochemistry …, 2020 - Springer
In this study, we purified and characterized flaxseed cysteine protease (FSCP) with strong
anticoagulant, antiplatelet, and clot-dissolving properties. The enzyme was purified to …