Advances in the pathogenesis of psoriasis: from keratinocyte perspective

X Zhou, Y Chen, L Cui, Y Shi, C Guo - Cell death & disease, 2022 - nature.com
Psoriasis is a complex long-lasting inflammatory skin disease with high prevalence and
associated comorbidity. It is characterized by epidermal hyperplasia and dermal infiltration …

Angiogenesis in chronic inflammatory skin disorders

HJ Lee, YJ Hong, M Kim - International Journal of Molecular Sciences, 2021 - mdpi.com
Angiogenesis, the growth of new blood vessels from preexisting vessels, is associated with
inflammation in various pathological conditions. Well-known angiogenetic factors include …

Current concepts of psoriasis immunopathogenesis

M Vičić, M Kaštelan, I Brajac, V Sotošek… - International Journal of …, 2021 - mdpi.com
Psoriasis is a recurrent, chronic, immune-mediated, systemic inflammatory disease of the
skin, joints, and other organic systems. After atopic dermatitis, chronic stationary psoriasis is …

Reactive oxygen species-responsive gel-based microneedle patches for prolonged and intelligent psoriasis management

D Bi, F Qu, W Xiao, J Wu, P Liu, H Du, Y Xie, H Liu… - ACS …, 2023 - ACS Publications
Psoriasis is an inflammatory skin disease. Microneedle (MN) patches can improve psoriasis
treatment outcomes by increasing local drug content in the skin. As psoriasis frequently …

Pathogenesis, multi-omics research, and clinical treatment of psoriasis

J Yu, Q Zhao, X Wang, H Zhou, J Hu, L Gu, Y Hu… - Journal of …, 2022 - Elsevier
Psoriasis is a common inflammatory skin disease involving interactions between
keratinocytes and immune cells that significantly affects the quality of life. It is characterized …

Keratinocyte: A trigger or an executor of psoriasis?

X Ni, Y Lai - Journal of Leucocyte Biology, 2020 - academic.oup.com
Psoriasis is a common chronic inflammatory skin disease characterized by abnormal
proliferation/differentiation of keratinocytes and excessive immune cell infiltration in the …

Updated perspectives on keratinocytes and psoriasis: keratinocytes are more than innocent bystanders

LI Ortiz-Lopez, V Choudhary… - Psoriasis: Targets and …, 2022 - Taylor & Francis
Psoriasis is a complex disease triggered by genetic, immunologic, and environmental
stimuli. Many genes have been linked to psoriasis, like the psoriasis susceptibility genes …

Cellular mechanisms of psoriasis pathogenesis: a systemic review

M Wu, C Dai, F Zeng - Clinical, cosmetic and investigational …, 2023 - Taylor & Francis
Psoriasis is a common inflammatory skin disease characterized by abnormal proliferation of
epidermal keratinocytes and massive infiltration of inflammatory cells. Many kinds of cells …

Regulatory T cells in angiogenesis

Z Lužnik, S Anchouche, R Dana, J Yin - The Journal of Immunology, 2020 - journals.aai.org
Regulatory T cells (Tregs) are crucial mediators of immune homeostasis. They regulate
immune response by suppressing inflammation and promoting self-tolerance. In addition to …

Human organ rejuvenation by VEGF-A: Lessons from the skin

A Keren, M Bertolini, Y Keren, Y Ullmann, R Paus… - Science …, 2022 - science.org
Transplanting aged human skin onto young SCID/beige mice morphologically rejuvenates
the xenotransplants. This is accompanied by angiogenesis, epidermal repigmentation, and …