Growing a circular economy with fungal biotechnology: a white paper
Fungi have the ability to transform organic materials into a rich and diverse set of useful
products and provide distinct opportunities for tackling the urgent challenges before all …
products and provide distinct opportunities for tackling the urgent challenges before all …
Moulding the mould: understanding and reprogramming filamentous fungal growth and morphogenesis for next generation cell factories
Filamentous fungi are harnessed as cell factories for the production of a diverse range of
organic acids, proteins, and secondary metabolites. Growth and morphology have critical …
organic acids, proteins, and secondary metabolites. Growth and morphology have critical …
Leveraging machine learning essentiality predictions and chemogenomic interactions to identify antifungal targets
Fungal pathogens pose a global threat to human health, with Candida albicans among the
leading killers. Systematic analysis of essential genes provides a powerful strategy to …
leading killers. Systematic analysis of essential genes provides a powerful strategy to …
[HTML][HTML] Strategies to establish the link between biosynthetic gene clusters and secondary metabolites
I Kjærbølling, UH Mortensen, T Vesth… - Fungal Genetics and …, 2019 - Elsevier
Filamentous fungi produce a vast number of bioactive secondary metabolites (SMs), some of
which have found applications in the pharmaceutical industry including as antibiotics and …
which have found applications in the pharmaceutical industry including as antibiotics and …
Understanding and controlling filamentous growth of fungal cell factories: novel tools and opportunities for targeted morphology engineering
Filamentous fungal cell factories are efficient producers of platform chemicals, proteins,
enzymes and natural products. Stirred-tank bioreactors up to a scale of several hundred m³ …
enzymes and natural products. Stirred-tank bioreactors up to a scale of several hundred m³ …
The regulatory and transcriptional landscape associated with carbon utilization in a filamentous fungus
Filamentous fungi, such as Neurospora crassa, are very efficient in deconstructing plant
biomass by the secretion of an arsenal of plant cell wall-degrading enzymes, by remodeling …
biomass by the secretion of an arsenal of plant cell wall-degrading enzymes, by remodeling …
Metabolomic and transcriptomic analyses reveal comparisons against liquid-state fermentation of primary dark tea, green tea and white tea by Aspergillus cristatus
Y Sun, X Yuan, Z Luo, Y Cao, S Liu, Y Liu - Food Research International, 2023 - Elsevier
Liquid-state fermentation (LSF) of tea leaves is a promising way to obtain tea-based
nutraceutical products rich in various bioactive compounds. In the study, the changes of …
nutraceutical products rich in various bioactive compounds. In the study, the changes of …
Multi-omics analysis of the metabolism of phenolic compounds in tea leaves by Aspergillus luchuensis during fermentation of pu-erh tea
Y Ma, B Jiang, K Liu, R Li, L Chen, Z Liu… - Food Research …, 2022 - Elsevier
Aspergillus fungi are extensively used in traditional food fermentation, so their functions,
mechanisms, and safety risks are worth exploring. In this study, a dominant fungal strain (P1) …
mechanisms, and safety risks are worth exploring. In this study, a dominant fungal strain (P1) …
[HTML][HTML] Genome-wide prediction and transcriptome analysis of sugar transporters in four ascomycete fungi
L Xu, J Li, VMG Ramos, C Lyra, A Wiebenga… - Bioresource …, 2024 - Elsevier
The import of plant-derived small sugars by sugar transporters (STs) has received
increasing interest due to its important biological role and great industrial potential. STs are …
increasing interest due to its important biological role and great industrial potential. STs are …
Something old, something new: challenges and developments in Aspergillus niger biotechnology
The filamentous ascomycete fungus Aspergillus niger is a prolific secretor of organic acids,
proteins, enzymes and secondary metabolites. Throughout the last century, biotechnologists …
proteins, enzymes and secondary metabolites. Throughout the last century, biotechnologists …