Fatty acids are metabolized and synthesized as energy substrates during biological
responses. Long-and medium-chain fatty acids derived mainly from dietary triglycerides, and …

Omega-3 polyunsaturated fatty acids (PUFAs) are considered immunonutrients and are
commonly used in the nutritional therapy of cancer patients due to their ample biological …

The G protein–coupled receptor 84 (GPR84), a medium-chain fatty acid receptor, has
garnered attention because of its potential involvement in a range of metabolic conditions …

Fatty acids (FFAs) are important biological molecules that serve as a major energy source
and are key components of biological membranes. In addition, FFAs play important roles in …

Therapeutic approaches to the treatment of type 2 diabetes mellitus that are designed to
increase insulin secretion either directly target β-cells or indirectly target gastrointestinal …

Obesity is characterized by a state of chronic inflammation in adipose tissue mediated by the
secretion of a range of inflammatory cytokines. In comparison to WAT, relatively little is …

25 years ago, the future of treating obesity and diabetes focused on end organs known to be
involved in energy balance and glucose regulation, including the brain, muscle, adipose …

Background Accumulating evidence links brown adipose tissue (BAT) to increased cold-
induced energy expenditure (CIEE) and regulation of lipid metabolism in humans. BAT has …

Scope Hepatic steatosis is a major health issue that can be attenuated by a healthy diet.
This study investigates the effects and molecular mechanisms of butyrate, a dietary fiber …

G protein-coupled receptor 120 (GPR120) and PPARγ agonists each have insulin
sensitizing effects. But whether these two pathways functionally interact and can be …