Blood-based biomarkers for Alzheimer's disease diagnosis and progression: an overview

A Varesi, A Carrara, VG Pires, V Floris, E Pierella… - Cells, 2022 - mdpi.com
Alzheimer's Disease (AD) is a progressive neurodegenerative disease characterized by
amyloid-β (Aβ) plaque deposition and neurofibrillary tangle accumulation in the brain …

Association of peripheral blood cell profile with Alzheimer's disease: a meta-analysis

LT Huang, CP Zhang, YB Wang… - Frontiers in Aging …, 2022 - frontiersin.org
Background Inflammation and immune dysfunction play significant roles in the pathogenesis
of Alzheimer's disease (AD)-related dementia. Changes in peripheral blood cell profiles are …

Proteome profiling of neuron-derived exosomes in Alzheimer's disease reveals hemoglobin as a potential biomarker

BI Arioz, KU Tufekci, M Olcum, DY Durur, BA Akarlar… - Neuroscience …, 2021 - Elsevier
Alzheimer's disease is a chronic and progressive neurodegenerative disorder, which is the
most common cause of dementia worldwide. Although amyloid plaques and neurofibrillary …

Proteomics for comprehensive characterization of extracellular vesicles in neurodegenerative disease

A Vinaiphat, SK Sze - Experimental neurology, 2022 - Elsevier
Extracellular vesicles (EVs) are small lipid bilayer particles ubiquitously released by almost
every cell type. A specific and selective constituents of EVs loaded with variety of proteins …

Circulating levels of vascular endothelial growth factor in patients with Alzheimer's disease: A case-control study

TMV da Silva, AM Stein, FG de Melo Coelho… - Behavioural Brain …, 2023 - Elsevier
Background Vascular endothelial growth factor (VEGF) and platelets seem to reflect the
Alzheimer's disease (AD) associated either with vascular impairment or disease. This study …

Blood levels of circulating methionine components in Alzheimer's disease and mild cognitive impairment: A systematic review and meta-analysis

Y Zhao, X Dong, B Chen, Y Zhang, S Meng… - Frontiers in Aging …, 2022 - frontiersin.org
Background Circulating methionine components have been reported to be associated with
Alzheimer's disease (AD) and mild cognitive impairment (MCI), although outcomes are not …

Reduced GLP-1R availability in the caudate nucleus with Alzheimer's disease

E Barrett, G Ivey, A Cunningham, G Coffman… - Frontiers in Aging …, 2024 - frontiersin.org
The glucagon-like peptide-1 receptor (GLP-1R) agonists reduce glycated hemoglobin in
patients with type 2 diabetes. Mounting evidence indicates that the potential of GLP-1R …

Complete blood count and systemic inflammation indices in individuals with Alzheimer's disease: A case-control study

JAG Tosatti, JD Pereira, CMG Loures, VG Fraga… - Journal of Clinical …, 2025 - Elsevier
Alzheimer's disease (AD) is the most common cause of dementia, characterized by
progressive cognitive and functional decline and is associated with aging. Chronic …

Nonlinear optical and photoacoustic properties of aqueous crystalline hemoglobin. Towards facile detection of hemoglobin concentration in blood

E Koushki, R Tayebee, M Esmaeili - Journal of Molecular Liquids, 2021 - Elsevier
In this work, nonlinear optical properties of hemoglobin are studied under the irradiation of a
blue LED laser beam. The z-scan setup is applied in order to determine nonlinear optical …

Relationships Between Treatment and Clinical Evaluations

P Celso Pardi, GAA dos Santos - Pharmacological Treatment of …, 2022 - Springer
The main symptoms of Alzheimer's disease and its relationship between treatment and
clinical evolution are strongly linked to a wide range of medical causes and are also …