Abstract Structure and function are highly correlated in the vertebrate retina, a sensory tissue
that is organized into cell layers with microcircuits working in parallel and together to encode …

The nervous system is populated by numerous types of neurons, each bearing a dendritic
arbor with a characteristic morphology. These type-specific features influence many aspects …

There are few neurochemical markers that reliably identify retinal ganglion cells (RGCs),
which are a heterogeneous population of cells that integrate and transmit the visual signal …

The molecular mechanisms mediating the retinogenic potential of multipotent retinal
progenitor cells (RPCs) are poorly defined. Prior to initiating retinogenesis, RPCs express a …

To establish functional circuitry, retinal neurons occupy spatial domains by arborizing their
processes, which requires the self-avoidance of neurites from an individual cell, and by …

In mice, all of the six retinal neuron types are generated from common multipotent retinal
progenitors, and their differentiation from progenitors is regulated by both extrinsic and …

In many parts of the nervous system, neuronal somata display orderly spatial arrangements.
In the retina, neurons of numerous individual subtypes form regular arrays called mosaics …

In the retina, like in most other brain regions, developing neurons are arranged into distinct
layers giving the mature tissue its stratified appearance. This process needs to be highly …

During CNS development, combinatorial expression of transcription factors controls
neuronal subtype identity and subsequent axonal trajectory. Regulatory genes designating …

LIM-homeodomain (HD) and POU-HD transcription factors play crucial roles in
neurogenesis. However, it remains largely unknown how they cooperate in this process and …