Modification of histidine repeat proteins by inorganic polyphosphate

N Neville, K Lehotsky, Z Yang, KA Klupt, A Denoncourt… - Cell Reports, 2023 - cell.com
Inorganic polyphosphate (polyP) is a linear polymer of orthophosphate that is present in
nearly all organisms studied to date. A remarkable function of polyP involves its attachment …

Recent Advances on Key Enzymes of Microbial Origin in the Lycopene Biosynthesis Pathway

B Du, M Sun, W Hui, C Xie, X Xu - Journal of Agricultural and Food …, 2023 - ACS Publications
Lycopene is a common carotenoid found mainly in ripe red fruits and vegetables that is
widely used in the food industry due to its characteristic color and health benefits. Microbial …

Splice modulators target PMS1 to reduce somatic expansion of the Huntington's disease-associated CAG repeat

ZL McLean, D Gao, K Correia, JCL Roy… - Nature …, 2024 - nature.com
Huntington's disease (HD) is a dominant neurological disorder caused by an expanded HTT
exon 1 CAG repeat that lengthens huntingtin's polyglutamine tract. Lowering mutant …

Pioneering DNA assembling techniques and their applications in eukaryotic microalgae

L Guo, G Yang - Biotechnology Advances, 2024 - Elsevier
Assembling DNA fragments is a fundamental manipulation of cloning microalgal genes and
carrying out microalgal synthetic biological studies. From the earliest DNA recombination to …

Assembly dynamics of FtsZ and DamX during infection-related filamentation and division in uropathogenic E. coli

B Söderström, MJ Pittorino, DO Daley… - Nature …, 2022 - nature.com
During infection of bladder epithelial cells, uropathogenic Escherichia coli (UPEC) can stop
dividing and grow into highly filamentous forms. Here, we find that some filaments of E. coli …

Translation of HIV-1 unspliced RNA is regulated by 5′ untranslated region structure

Z Cheng, S Islam, JG Kanlong, M Sheppard… - Journal of …, 2024 - journals.asm.org
ABSTRACT HIV-1 must generate infectious virions to spread to new hosts and HIV-1
unspliced RNA (HIV-1 RNA) plays two central roles in this process. HIV-1 RNA serves as an …

Multiple pkd and piezo gene family members are required for atrioventricular valve formation

T Juan, A Ribeiro da Silva, B Cardoso, SE Lim… - Nature …, 2023 - nature.com
Cardiac valves ensure unidirectional blood flow through the heart, and altering their function
can result in heart failure. Flow sensing via wall shear stress and wall stretching through the …

Caspase-1 activates gasdermin A in non-mammals

ZP Billman, SB Kovacs, B Wei, K Kang, OH Cissé… - ELife, 2024 - elifesciences.org
Gasdermins oligomerize to form pores in the cell membrane, causing regulated lytic cell
death called pyroptosis. Mammals encode five gasdermins that can trigger pyroptosis …

[HTML][HTML] Caspase-1 activates gasdermin A in all non-mammals

ZP Billman, SB Kovacs, B Wei, K Kang, OH Cissé… - eLife, 2023 - elifesciences.org
Gasdermins oligomerize to form pores in the cell membrane, causing programmed lytic cell
death called pyroptosis. Mammals encode five gasdermins that can trigger pyroptosis …

Development of a set of novel binary expression vectors for plant gene function analysis and genetic transformation

X Wang, C Teng, H Wei, S Liu, H Xuan… - Frontiers in Plant …, 2023 - frontiersin.org
With the advent of multiple omics and Genome-Wide Association Studies (GWAS)
technology, genome-scale functional analysis of candidate genes is to be conducted in …