microRNAs biogenesis, functions and role in tumor angiogenesis

T Annese, R Tamma, M De Giorgis, D Ribatti - Frontiers in oncology, 2020 - frontiersin.org
microRNAs (miRNAs) are small non-coding RNA molecules, evolutionary conserved. They
target more than one mRNAs, thus influencing multiple molecular pathways, but also …

Small nucleolar RNAs: insight into their function in cancer

J Liang, J Wen, Z Huang, X Chen, B Zhang… - Frontiers in …, 2019 - frontiersin.org
Small nucleolar RNAs (SnoRNAs) are a class of non-coding RNAs divided into two classes:
C/D box snoRNAs and H/ACA box snoRNAs. The canonical function of C/D box and H/ACA …

Emerging functions for snoRNAs and snoRNA-derived fragments

M Wajahat, CP Bracken, A Orang - International journal of molecular …, 2021 - mdpi.com
The widespread implementation of mass sequencing has revealed a diverse landscape of
small RNAs derived from larger precursors. Whilst many of these are likely to be byproducts …

A pan-cancer analysis of the expression and clinical relevance of small nucleolar RNAs in human cancer

J Gong, Y Li, C Liu, YU Xiang, C Li, Y Ye, Z Zhang… - Cell reports, 2017 - cell.com
Increasing evidence has demonstrated that small nucleolar RNAs (snoRNAs) play important
roles in tumorigenesis. We systematically investigated the expression landscape and clinical …

[HTML][HTML] A comprehensive repertoire of tRNA-derived fragments in prostate cancer

M Olvedy, M Scaravilli, Y Hoogstrate, T Visakorpi… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Prostate cancer (PCa) is the most common cancer among men in developed countries.
Although its genetic background is thoroughly investigated, rather little is known about the …

[HTML][HTML] Non-coding RNAs: the riddle of the transcriptome and their perspectives in cancer

MA Diamantopoulos, P Tsiakanikas… - Annals of translational …, 2018 - ncbi.nlm.nih.gov
Non-coding RNAs (ncRNAs) constitute a heterogeneous group of RNA molecules in terms
of biogenesis, biological function as well as length and structure. These biological …

SnoRNA in cancer progression, metastasis and immunotherapy response

J van der Werf, CV Chin, NI Fleming - Biology, 2021 - mdpi.com
Simple Summary A much larger number of small nucleolar RNA (snoRNA) have been found
encoded within our genomes than we ever expected to see. The activities of the snoRNAs …

SNORD126 promotes HCC and CRC cell growth by activating the PI3K–AKT pathway through FGFR2

X Fang, D Yang, H Luo, S Wu, W Dong… - Journal of molecular …, 2017 - academic.oup.com
Small nucleolar RNA (snoRNA) dysfunctions have been associated with cancer
development. SNORD126 is an orphan C/D box snoRNA that is encoded within introns 5–6 …

Non-coding RNAs: Emerging from the discovery to therapeutic applications

B Baptista, M Riscado, JA Queiroz, C Pichon… - Biochemical …, 2021 - Elsevier
The knowledge about non-coding RNAs (ncRNAs) is rapidly increasing with new data
continuously emerging, regarding their diverse types, applications, and roles. Particular …

C/D‐box snoRNAs form methylating and non‐methylating ribonucleoprotein complexes: Old dogs show new tricks

M Falaleeva, JR Welden, MJ Duncan, S Stamm - Bioessays, 2017 - Wiley Online Library
C/D box snoRNAs (SNORDs) are an abundantly expressed class of short, non‐coding
RNAs that have been long known to perform 2′‐O‐methylation of rRNAs. However …