Development of virus‐like particles‐based vaccines against coronaviruses

CY Yong, WPP Liew, HK Ong… - Biotechnology Progress, 2022 - Wiley Online Library
Severe acute respiratory syndrome coronavirus (SARS‐CoV), Middle East respiratory
syndrome coronavirus (MERS‐CoV), and the current severe acute respiratory syndrome …

Progress in the development of universal influenza vaccines

W Sun, T Luo, W Liu, J Li - Viruses, 2020 - mdpi.com
Influenza viruses pose a significant threat to human health. They are responsible for a large
number of deaths annually and have a serious impact on the global economy. There are …

Influenza virus like particles (VLPs): opportunities for H7N9 vaccine development

P Pushko, I Tretyakova - Viruses, 2020 - mdpi.com
In the midst of the ongoing COVID-19 coronavirus pandemic, influenza virus remains a
major threat to public health due to its potential to cause epidemics and pandemics with …

Respiratory viruses and virus-like particle vaccine development: how far have we advanced?

KB Chu, FS Quan - Viruses, 2023 - mdpi.com
With technological advancements enabling globalization, the intercontinental transmission
of pathogens has become much easier. Respiratory viruses are one such group of …

Development of an mRNA vaccine against a panel of heterologous H1N1 seasonal influenza viruses using a consensus hemagglutinin sequence

N Ma, ZW Xia, ZG Zhang, XX Nian, XD Li… - Emerging Microbes & …, 2023 - Taylor & Francis
Seasonal influenza, causes hundreds of thousands of deaths annually, posing a severe
threat to human health. Currently available influenza vaccines are targeted only at specific …

Next-generation viral nanoparticles for targeted delivery of therapeutics: Fundamentals, methods, biomedical applications, and challenges

JS Tan, MNB Jaffar Ali, BK Gan… - Expert Opinion on Drug …, 2023 - Taylor & Francis
ABSTRACT Introduction Viral nanoparticles (VNPs) are virus-based nanocarriers that have
been studied extensively and intensively for biomedical applications. However, their clinical …

Virus-like particle vaccines: A prospective panacea against an avian influenza panzootic

NN Ninyio, KL Ho, AR Omar, WS Tan, M Iqbal… - Vaccines, 2020 - mdpi.com
Epizootics of highly pathogenic avian influenza (HPAI) have resulted in the deaths of
millions of birds leading to huge financial losses to the poultry industry worldwide. The roles …

Advances in protein subunit vaccines against H1N1/09 influenza

Y Zhang, J Gao, W Xu, X Huo, J Wang, Y Xu… - Frontiers in …, 2024 - frontiersin.org
The A/H1N1pdm09 influenza virus, which caused the 2009 pandemic, has since become a
recurring strain in seasonal influenza outbreaks. Given the ongoing threat of influenza …

A simple and high efficiency purification of His-tagged turnip yellow mosaic virus-like particle (TYMV-VLP) by nickel ion affinity precipitation

FH Tan, JF Ng, NBM Alitheen, A Muhamad… - Journal of Virological …, 2023 - Elsevier
Virus-like particles (VLPs) is one of the most favourable subjects of study, especially in the
field of nanobiotechnology and vaccine development because they possess good …

Broadly cross-reactive immune responses in chickens immunized with chimeric virus-like particles of nodavirus displaying the M2e originated from avian and human …

BYZ Thian, MNN Fatimah, CL Wong, HK Ong… - Developmental & …, 2025 - Elsevier
Avian influenza A viruses (IAVs) pose a persistent threat to poultry industry worldwide,
despite the presence of vaccines. Additionally, reverse-zoonosis transmission potentially …