Despite the applicability of histone deacetylase inhibitors (HDACis) for cancer treatment,
several works in the literature have shown that these inhibitors can be used in several other …

The immediate early gene, Arc, is a pivotal regulator of synaptic plasticity, memory, and
cognitive flexibility. But what is Arc protein? How does it work? Inside the neuron, Arc is a …

Activity‐regulated cytoskeleton‐associated protein (Arc) is a protein interaction hub with
diverse roles in intracellular neuronal signaling, and important functions in neuronal …

Sleep deprivation is a global health problem adversely affecting health as well as causing
decrements in learning and performance. Sleep deprivation induces significant changes in …

Aims The current evidence demonstrates that mesenchymal stem cells (MSCs) hold
therapeutic potential for ischemic stroke. However, it remains unclear how changes in the …

Brain-derived neurotrophic factor (BDNF) is essential for cognitive and memory functions.
Abnormal BDNF expression in the central nervous system may impair these functions …

Through epigenetic and other regulatory functions, the histone deacetylase (HDAC) family of
enzymes has emerged as a promising therapeutic target for central nervous system and …

Recent studies show that histone deacetylase 6 (HDAC6) has important roles in the human
brain, especially in the context of a number of nervous system disorders. Animal models of …

Activity‐regulated cytoskeleton‐associated protein (Arc) is an immediate early gene product
that support neuroplastic changes important for cognitive function and memory formation. As …

Loss of fragile X retardation protein (FMRP) leads to fragile X syndrome (FXS), a common
cause of inherited intellectual disability. Protein lysine acetylation (K-ac), a reversible post …