Alzheimer's disease (AD) is the most common cause of dementia associated with a
progressive neurodegenerative disorder, with a prevalence of 44 million people throughout …

Parkinson's disease (PD) is the second most frequent neurodegenerative brain disease
(NBD) after Alzheimer's disease (AD). Statins are the most common lipid‐lowering agents …

Alzheimer's disease (AD) is a neurodegenerative disorder that is one of the most
devastating and widespread diseases worldwide, mainly affecting the aging population. One …

Cholesterol is important for normal brain function. The brain synthesizes its own cholesterol,
presumably in astrocytes. We have previously shown that diabetes results in decreased …

Significant knowledge about the pathophysiology of Alzheimer's disease (AD) has been
gained in the last century; however, the understanding of its causes of onset remains limited …

In Alzheimer's disease (AD), both cholesterol and glucose dysmetabolism precede the onset
of memory deficit and contribute to the disease's progression. It is indeed now believed that …

Statins are more widely used not only for the primary and secondary prevention of
cardiovascular disease by blocking cholesterol biosynthesis but also for the potential …

Although different regions of the brain are dedicated to specific functions, the intra-and inter-
regional heterogeneity of astrocytes and microglia in these regions has not yet been fully …

Osteoporosis and Alzheimer's disease (AD) are both degenerative diseases. Osteoporosis
often proceeds cognitive deficits, and multiple studies have revealed common triggers that …

The discovery of contact sites was a breakthrough in cell biology. We have learned that an
organelle cannot function in isolation, and that many cellular functions depend on …