The origin story and emergence of molecular biology is muddled. The early triumphs in
bacterial genetics and the complexity of animal and plant genomes complicate an intricate …

RNA interference (RNAi) plays pleiotropic roles in animal cells, from the post-transcriptional
control of gene expression via the production of micro-RNAs, to the inhibition of RNA virus …

There is increasing interest among cancer researchers in the study of Piwi-interacting RNAs
(piRNAs), a group of small RNAs important for maintaining genome stability in the germline …

Aging is a multifactorial process characterized by an age-related decline in organismal
fitness. This deterioration is the major risk factor for chronic diseases such as cardiovascular …

The adult neurogenic niches are complex multicellular systems, receiving regulatory input
from a multitude of intracellular, juxtacrine, and paracrine signals and biological pathways …

The pathological hallmark of the majority of amyotrophic lateral sclerosis (ALS) cases is the
mislocalization and aggregation of TAR DNA-binding protein 43 (TDP-43), an RNA-binding …

Increasing evidence reinforces the essential function of RNA modifications in development
and diseases, especially in the nervous system. RNA modifications impact various …

Tissue regeneration requires precise temporal control of cellular processes such as
inflammatory signaling, chromatin remodeling and proliferation. The combination of these …

PIWI-interacting RNAs (piRNAs) are small non-coding RNAs that bind to the PIWI subclass
of the Argonaute protein family and are essential for maintaining germline integrity. Initially …

PIWI-interacting RNAs (piRNAs), a class of small non-coding RNAs (sncRNAs) with 24–32
nucleotides (nt), were initially identified in the reproductive system. Unlike microRNAs …