Malaria therapeutics: are we close enough?

H Tripathi, P Bhalerao, S Singh, H Arya, BS Alotaibi… - Parasites & …, 2023 - Springer
Malaria is a vector-borne parasitic disease caused by the apicomplexan protozoan parasite
Plasmodium. Malaria is a significant health problem and the leading cause of …

Microfluidic devices for the detection of disease-specific proteins and other macromolecules, disease modelling and drug development: A review

S Amir, A Arathi, S Reshma, PV Mohanan - International Journal of …, 2023 - Elsevier
Microfluidics is a revolutionary technology that has promising applications in the biomedical
field. Integrating microfluidic technology with the traditional assays unravels the innumerable …

[HTML][HTML] Insights into microfabrication and implementation of microfluidics in pharmaceutical drug delivery and analysis

OA Al-wdan, OA Sharallah, NA Abdelwahab… - OpenNano, 2023 - Elsevier
Microfluidics are systems that set forth valuable means to efficiently control fluid movement
and dynamics in specially fabricated micro-channel systems. The advancement of the …

Analytical and biomedical applications of microfluidics in traditional Chinese medicine research

P Shen, Y Jia, S Shi, J Sun, X Han - TrAC Trends in Analytical Chemistry, 2023 - Elsevier
Traditional Chinese medicine (TCM) has significant benefits in the prevention and treatment
of diseases due to its unique theoretical system and research techniques. However, there …

Hemozoin in malaria eradication—from material science, technology to field test

A Rathi, Z Chowdhry, A Patel, S Zuo, TCP Veettil… - NPG Asia …, 2023 - nature.com
Malaria continues to be among the most lethal infectious diseases. Immediate barriers
include the detection of low-parasitemia levels in asymptomatic individuals, which act as a …

A versatile microfluidic platform for malaria infection screening and Plasmodium species genotyping

L Xiu, H Li, Q Hu, Y Zhang, SB Chen, C Wang… - Ebiomedicine, 2023 - thelancet.com
Background Malaria, a widespread parasitic disease caused by Plasmodium species,
remains a significant global health concern. Rapid and accurate detection, as well as …

Malaria: biochemical, physiological, diagnostic, and therapeutic updates

E El Saftawy, MF Farag, HH Gebreil, M Abdelfatah… - PeerJ, 2024 - peerj.com
Background Malaria has been appraised as a significant vector-borne parasitic disease with
grave morbidity and high-rate mortality. Several challenges have been confronting the …

Impedance-based rapid diagnostic tool for single malaria parasite detection

M Giacometti, T Pravettoni, J Barsotti… - … Circuits and Systems, 2022 - ieeexplore.ieee.org
This paper presents a custom, low-cost electronic system specifically designed for rapid and
quantitative detection of the malaria parasite in a blood sample. The system exploits the …

Lab on a chip (LOC) platform for drug screening against the intracellular forms of Trypanosoma cruzi

MF Cadena, G Rosero-Yanez, R Isa-Jara… - Microchemical …, 2024 - Elsevier
Trypanosoma cruzi is the etiological agent of Chagas disease, endemic in Latin America
with recent spreading to non-endemic areas due to human migration. The low efficacy and …

Numerical simulation of optical refractometric sensing of multiple disease markers based on lab-in-a-fiber

Z Zheng, Z Li, Q Du - Optics Express, 2022 - opg.optica.org
A multi-parameter optical refractometric sensor based on lab-in-a-fiber is proposed and its
sensing properties have been investigated. Based on the particular three suspended-core …