Lipid vesicles can provide a cost-effective enhancement of skin drug absorption when
vesicle production process is optimised. It is an important challenge to design the ideal …

The demand for halal cosmetic products among the 2.4 billion Muslim consumers worldwide
is increasing. However, the demand for halal cosmetics remains unmet because cosmetics …

Polymeric micelles, which form through the self-assembly of poly (ethylene glycol)–poly
(amino acid) block copolymers, are systemic nanocarriers in targeted cancer therapy. These …

Triamcinolone acetonide (TA) is an effective drug widely (off-label) used in the treatment of
several ocular diseases involving inflammation and angiogenic processes. However, the …

A molecular-level understanding of skin permeation may rationalize and streamline product
development, and improve quality and control, of transdermal and topical drug delivery …

To measure progress and evaluate performance of the newest UB/UC/P&G skin penetration
model we simulated an 18-compound subset of finite dose in vitro human skin permeation …

Gingiva or gum is a part of the periodontium that surrounds the tooth. Its main function is to
provide an effective barrier to both mechanical trauma and bacterial invasion. Gingiva is the …

This study probes the mechanisms by which volatile solvents (water, ethanol) and a
nonionic surfactant (Triton X-100) influence the skin permeation of dissolved solutes …

Background Although the quality by design (QbD) approach is widely used to develop
pharmaceutical products and to consistently ensure and improve product quality, studies on …

Purpose Presented is the development of a workflow for end-to-end (e2e) in silico modelling
of percutaneous absorption under a range of test conditions, integrating multiple calculation …