Tissue engineering aims to structurally and functionally regenerate damaged tissues, which
requires the formation of new blood vessels that supply oxygen and nutrients by the process …

Inflammation is a key factor in multiple diseases including primary immune-mediated
inflammatory diseases eg rheumatoid arthritis but also, less obviously, in many other …

Injection of recombinant tissue plasminogen activator (rt-PA) is the standard drug treatment
for thrombolysis. However, rt-PA shows risk of hemorrhages and limited efficiency even at …

Microbubbles (MB) are routinely used as contrast agents for ultrasound (US) imaging. We
describe different types of targeted and drug-loaded poly (n-butyl cyanoacrylate)(PBCA) MB …

Blood vessel functionality is crucial for efficient tumor-targeted drug delivery. Heterogeneous
distribution and perfusion of angiogenic blood vessels contribute to suboptimal …

Identifying intended or accidental cellular targets for drug delivery systems is highly relevant
for evaluating therapeutic and toxic effects. However, limited knowledge exists on the …

Microbubbles (MB) are used as ultrasound (US) contrast agents and can be efficiently
targeted against markers of angiogenesis and inflammation. Due to their gas core, MB …

Thrombotic diseases rarely cause symptoms until advanced stage and sudden death. Thus,
early detection of thrombus by a widely spread imaging modality can improve the prognosis …

Ultrasound (US) imaging of heart and major arteries and veins is among the most frequently
used diagnostic techniques applied in humans. Conventional cardiovascular US sessions …

The above studies relied on subjective assessment of the extent of neovascularization on
CEUS. To improve this, the dynamic cine clip-based time-intensity curve for wash-in time of …