CD146 was originally identified as a melanoma cell adhesion molecule (MCAM) and highly
expressed in many tumors and endothelial cells. However, the evidence that CD146 acts as …

Laminins are large molecular weight glycoproteins constituted by the assembly of three
disulfide-linked polypeptides, the α, β and γ chains. The human genome encodes 11 …

The extracellular matrix (ECM) is critical for all aspects of vascular biology. In concert with
supporting cells, endothelial cells (ECs) assemble a laminin-rich basement membrane …

Endothelial cells of the blood and lymphatic vasculature are polarized cells with luminal
surfaces specialized to interact with inflammatory cells upon the appropriate stimulation; …

Laminins, one of the major functional components of basement membranes, are found
underlying endothelium, and encasing pericytes and smooth muscle cells in the vessel wall …

The interactions of cells with basement membranes are primarily mediated via the
engagement of laminins by a group of integrin family proteins, including integrins α3β1 …

The hair follicle bulge in the epidermis associates with the arrector pili muscle (APM) that is
responsible for piloerection (" goosebumps"). We show that stem cells in the bulge deposit …

Platelets play a variety of roles in vascular biology and are best recognized as primary
hemostasis and thrombosis mediators. Platelets have a large number of receptors and …

Laminins are a growing family of αβγ heterotrimeric proteins, commonly found in basement
membranes (BMs). These large molecules promote cell adhesion and migration via …

INTRODUCTION The function of the brain relies on communication among the complex
network of cells that constitute this organ. Vascularization of the central nervous system …