TGFβ signalling has key roles in cancer progression: most carcinoma cells have inactivated
their epithelial antiproliferative response and benefit from increased TGFβ expression and …

Epithelial ovarian cancer (EOC) is a leading cause of cancer-related death in women. Late-
stage diagnosis with significant tumor burden, accompanied by recurrence and …

Adoptive transfer of genetically modified immune cells holds great promise for cancer
immunotherapy. CRISPR knockin targeting can improve cell therapies, but more high …

While checkpoint blockade immunotherapies have widespread success, they rely on a
responsive immune infiltrate; as such, treatments enhancing immune infiltration and …

Transforming growth factor β (TGFβ) is a major component of tumor‐derived small
extracellular vesicles (TEX) in cancer patients. Mechanisms utilized by TGFβ+ TEX to …

Anti-Müllerian hormone (AMH), or Müllerian-inhibiting substance, is a protein hormone that
promotes Müllerian duct regression during male fetal sexual differentiation and regulation of …

Adoptive cell therapy with chimeric antigen receptor (CAR)-redirected T cells induced
spectacular regressions of leukemia and lymphoma, however, failed so far in the treatment …

Microcrystal electron diffraction (MicroED) has recently shown potential for structural biology.
It enables the study of biomolecules from micrometer-sized 3D crystals that are too small to …

The increasing cyanobacterial blooms have recently been considered a severe
environmental problem. Microcystin-leucine arginine (MC-LR) is one of the secondary …

Transforming growth factor beta (TGF-β) is an important growth factor that plays essential
roles in regulating tissue development and homeostasis. Dysfunction of TGF-β signaling is a …