▪ Abstract Completion of the cell cycle requires the temporal and spatial coordination of
chromosome segregation with mitotic spindle disassembly and cytokinesis. In budding …

The “Hippo” signaling pathway has emerged as a major regulator of cell proliferation and
survival in metazoans. The pathway, as delineated by genetic and biochemical studies in …

Coordination between cell proliferation and cell death is essential to maintain homeostasis
in multicellular organisms. In Drosophila, these two processes are regulated by a pathway …

Cytokinesis is a temporally and spatially regulated process through which the cellular
constituents of the mother cell are partitioned into two daughter cells, permitting an increase …

Cell division requires careful orchestration of three major events: entry into mitosis,
chromosomal segregation, and cytokinesis. Signaling within and between the molecules …

Members of the NDR (nuclear Dbf2-related) protein-kinase family are essential components
of pathways that control important cellular processes, such as morphological changes …

A conserved signalling cascade—termed the mitotic-exit network in budding yeast and the
septation-initiation network in fission yeast—controls key events during exit from mitosis and …

Septins are conserved GTP-binding proteins that assemble into hetero-oligomeric
complexes and higher-order structures such as filaments, rings, hourglasses or gauzes …

▪ Abstract Cytokinesis creates two daughter cells endowed with a complete set of
chromosomes and cytoplasmic organelles. This conceptually simple event is mediated by a …

Early observations of centrosomes, made a century ago, revealed a tiny dark structure
surrounded by a radial array of cytoplasmic fibers. We now know that the fibers are …