Coronary artery disease represents the leading cause of death worldwide, sparing no
nation, ethnicity, or economic stratum. Coronary artery disease is partly heritable. While …

The genetic architecture of blood pressure (BP) now includes more than 30 genes, with rare
mutations resulting in inherited forms of hypertension or hypotension, and 1477 common …

Spontaneous coronary artery dissection (SCAD) is a non-atherosclerotic cause of
myocardial infarction (MI), typically in young women. We undertook a genome-wide …

Despite the great success of genome-wide association studies (GWAS) in identifying genetic
loci significantly associated with diseases, the vast majority of causal variants underlying …

Fibromuscular dysplasia (FMD) is an arteriopathy associated with hypertension, stroke and
myocardial infarction, affecting mostly women. We report results from the first genome-wide …

Importance Spontaneous coronary artery dissection (SCAD), an idiopathic disorder that
predominantly affects young to middle-aged women, has emerged as an important cause of …

Background and Objectives Migraine, stroke, and cervical artery dissection (CeAD)
represent a triad of cerebrovascular disorders with pairwise comorbid relationships and …

Efferocytosis, the process through which apoptotic cells (ACs) are cleared through actin-
mediated engulfment by macrophages, prevents secondary necrosis, suppresses …

Background: Calcific aortic valve stenosis (CAVS) is a frequent and life-threatening
cardiovascular disease for which there is currently no medical treatment available. To date …

Multifocal fibromuscular dysplasia (FMD) and spontaneous coronary artery dissection are
both sex-biased diseases disproportionately affecting women over men in a 9: 1 ratio …