Asymmetric organocatalysis is now recognized as the third pillar of asymmetric synthesis.
Recent years have witnessed increasing interest towards the use of highly active and …

α-Imino esters are useful precursors for the synthesis of a variety of types of natural and
unnatural α-amino acid derivatives, with a wide range of biological activities. Due to the …

This paper purports to review catalysis, particularly the organocatalysis and its origin, key
trends, challenges, examples, scope, and importance. The definition of organocatalyst …

Sustainability concerns are the wind in the sails for the development of novel, more selective
catalytic processes. Hence, chiral catalysts play a crucial role in the green production of …

Asymmetric aldol reactions catalyzed by a novel polystyrene‐immobilized proline derivative
occur in short reaction times with excellent diastereo‐and enantioselectivity. The catalyst …

Sustainability concerns are reshaping the way chemists work, not only at the stage of
process design, but also when actually performing reactions. This change in outlook is …

A simple and novel solid-supported organocatalyst from a 2-chlorotrityl chloride resin-
immobilized 4-hydroxyproline was developed, and this organocatalyst has been used for the …

A polystyrene-supported, pyrrolidine-based catalyst depicting very high activity and
excellent stereoselectivity in the anti-Mannich reaction of aldehydes and ketones has been …

A series of primary amino acid-derived polystyrene-supported organocatalysts was tested in
anti-selective Mannich reactions. The polystyrene-immobilized threonine derivative showed …

A range of protected γ-oxo-α-amino esters have been prepared in a highly regio-and
stereoselective manner through the decarboxylative Mannich reaction of β-keto acids with …