[HTML][HTML] Circular RNAs in cancer
Circular RNAs (circRNAs) are a class of single-stranded closed RNA molecules that are
formed by precursor mRNA back-splicing or skipping events of thousands of genes in …
formed by precursor mRNA back-splicing or skipping events of thousands of genes in …
Niacin in the central nervous system: an update of biological aspects and clinical applications
V Gasperi, M Sibilano, I Savini, MV Catani - International journal of …, 2019 - mdpi.com
Niacin (also known as “vitamin B3” or “vitamin PP”) includes two vitamers (nicotinic acid and
nicotinamide) giving rise to the coenzymatic forms nicotinamide adenine dinucleotide (NAD) …
nicotinamide) giving rise to the coenzymatic forms nicotinamide adenine dinucleotide (NAD) …
Circular RNAs as biomarkers and therapeutic targets in cancer
A Beilerli, I Gareev, O Beylerli, G Yang, V Pavlov… - Seminars in cancer …, 2022 - Elsevier
Circular RNAs (circRNAs) are a class of single-stranded closed non-coding RNA molecules
(ncRNAs), which are formed as a result of reverse splicing of mRNAs. Despite their relative …
(ncRNAs), which are formed as a result of reverse splicing of mRNAs. Despite their relative …
The role of platelets in the tumor-microenvironment and the drug resistance of cancer cells
PT Huong, LT Nguyen, XB Nguyen, SK Lee, DH Bach - Cancers, 2019 - mdpi.com
Besides the critical functions in hemostasis, thrombosis and the wounding process, platelets
have been increasingly identified as active players in various processes in tumorigenesis …
have been increasingly identified as active players in various processes in tumorigenesis …
Potent Inhibition of Nicotinamide N-Methyltransferase by Alkene-Linked Bisubstrate Mimics Bearing Electron Deficient Aromatics
Y Gao, MJ Van Haren, N Buijs, P Innocenti… - Journal of Medicinal …, 2021 - ACS Publications
Nicotinamide N-methyltransferase (NNMT) methylates nicotinamide (vitamin B3) to generate
1-methylnicotinamide (MNA). NNMT overexpression has been linked to a variety of …
1-methylnicotinamide (MNA). NNMT overexpression has been linked to a variety of …
Current developments in nanotechnology for improved cancer treatment, focusing on tumor hypoxia
Hypoxia is a common feature of the tumor microenvironment, which is characterized by
tissue oxygen deficiency due to an aggressive proliferation of cancer cells. Hypoxia …
tissue oxygen deficiency due to an aggressive proliferation of cancer cells. Hypoxia …
PTEN in lung cancer: dealing with the problem, building on new knowledge and turning the game around
A Gkountakos, G Sartori, I Falcone, G Piro, L Ciuffreda… - Cancers, 2019 - mdpi.com
Lung cancer is the most common malignancy and cause of cancer deaths worldwide, owing
to the dismal prognosis for most affected patients. Phosphatase and tensin homolog deleted …
to the dismal prognosis for most affected patients. Phosphatase and tensin homolog deleted …
Chromosomal instability in tumor initiation and development
Chromosomal instability (CIN) is one of the major forms of genomic instability in various
human cancers and is recognized as a common hallmark of tumorigenesis and …
human cancers and is recognized as a common hallmark of tumorigenesis and …
The dominant role of forkhead box proteins in cancer
Forkhead box (FOX) proteins are multifaceted transcription factors that are significantly
implicated in cancer, with various critical roles in biological processes. Herein, we provide …
implicated in cancer, with various critical roles in biological processes. Herein, we provide …
Small in size, but large in action: microRNAs as potential modulators of PTEN in breast and lung cancers
AJ Abadi, A Zarrabi, MH Gholami, S Mirzaei… - Biomolecules, 2021 - mdpi.com
MicroRNAs (miRNAs) are well-known regulators of biological mechanisms with a small size
of 19–24 nucleotides and a single-stranded structure. miRNA dysregulation occurs in cancer …
of 19–24 nucleotides and a single-stranded structure. miRNA dysregulation occurs in cancer …