Microglia, the immunocompetent cells of the central nervous system (CNS), act as
neuropathology sensors and are neuroprotective under physiological conditions. Microglia …

Resident microglial cells can be regarded as the immunological watchdogs of the brain and
the retina. They are active sensors of their neuronal microenvironment and rapidly respond …

Microglia play an important role in the pathology of CNS disorders, however, there remains
significant uncertainty about the neuroprotective/degenerative role of these cells due to a …

Traumatic optic neuropathy (TON) refers to a pathological condition caused by a direct or
indirect insult to the optic nerves, which often leads to a partial or permanent vision deficit …

Microglia, the resident immune cells of the brain and retina, are constantly engaged in the
surveillance of their surrounding neural tissue. During embryonic development they infiltrate …

Retinal degenerative diseases are major causes of vision loss and blindness worldwide and
are characterized by chronic and progressive neuronal loss. One common feature of retinal …

Microglia are the main resident immune cells of the nervous system and as such they are
involved in multiple roles ranging from tissue homeostasis to response to insults and circuit …

Immune functions in the brain are associated with psychiatric illness and temporary
alteration of mental state. Microglia, the principal brain immunologic cells, respond to …

Background Glaucomatous optic neuropathy, a leading cause of blindness, can progress
despite control of intraocular pressure-currently the main risk factor and target for treatment …

Microglia are the resident immune cells of the central nervous system (CNS) and play a key
role in maintaining the normal function of the retina and brain. During early development …