Human and environmental impacts of nanoparticles: a scoping review of the current literature

EA Kumah, RD Fopa, S Harati, P Boadu, FV Zohoori… - BMC Public Health, 2023 - Springer
Use of nanoparticles have established benefits in a wide range of applications, however, the
effects of exposure to nanoparticles on health and the environmental risks associated with …

Beyond PM2. 5: The role of ultrafine particles on adverse health effects of air pollution

R Chen, B Hu, Y Liu, J Xu, G Yang, D Xu… - Biochimica et Biophysica …, 2016 - Elsevier
Background Air pollution constitutes the major threat to human health, whereas their
adverse impacts and underlying mechanisms of different particular matters are not clearly …

Air-Liquid Interface: Relevant In Vitro Models for Investigating Air Pollutant-Induced Pulmonary Toxicity

S Upadhyay, L Palmberg - Toxicological Sciences, 2018 - academic.oup.com
Air pollution leads to inhalation of several pulmonary stimulants that includes particulate
matter, and gaseous substances contributing significantly to the development of chronic lung …

Nanotoxicology: an interdisciplinary challenge

HF Krug, P Wick - Angewandte Chemie International Edition, 2011 - Wiley Online Library
The increasing consumption of products containing nanomaterials that can be currently
observed and forecasts of new developments and applications fan the fear of individuals …

[HTML][HTML] t4 workshop report: State-of-the-art of 3D cultures (organs-on-a-chip) in safety testing and pathophysiology

N Alépée, A Bahinski, M Daneshian, B De Wever… - Altex, 2014 - ncbi.nlm.nih.gov
Integrated approaches using different in vitro methods in combination with bioinformatics
can (i) increase the success rate and speed of drug development;(ii) improve the accuracy of …

In-vitro cell exposure studies for the assessment of nanoparticle toxicity in the lung—A dialog between aerosol science and biology

HR Paur, FR Cassee, J Teeguarden, H Fissan… - Journal of aerosol …, 2011 - Elsevier
The introduction of engineered nanostructured materials into a rapidly increasing number of
industrial and consumer products will result in enhanced exposure to engineered …

Assessing nanoparticle toxicity in cell-based assays: influence of cell culture parameters and optimized models for bridging the in vitro–in vivo gap

F Joris, BB Manshian, K Peynshaert… - Chemical Society …, 2013 - pubs.rsc.org
The number of newly engineered nanomaterials is vastly increasing along with their
applications. Despite the fact that there is a lot of interest and effort is being put into the …

[HTML][HTML] In vitro and ex vivo models in inhalation biopharmaceutical research—advances, challenges and future perspectives

MA Selo, JA Sake, KJ Kim, C Ehrhardt - Advanced Drug Delivery Reviews, 2021 - Elsevier
Oral inhalation results in pulmonary drug targeting and thereby reduces systemic side
effects, making it the preferred means of drug delivery for the treatment of respiratory …

Size dependent macrophage responses and toxicological effects of Ag nanoparticles

J Park, DH Lim, HJ Lim, T Kwon, J Choi… - Chemical …, 2011 - pubs.rsc.org
The immune-response of macrophages is an important area of investigation since it
represents the major pathway by which early-stage defense barriers are established in skin …

Toxicity Research of PM2.5 Compositions in Vitro

YY Jia, Q Wang, T Liu - … journal of environmental research and public …, 2017 - mdpi.com
According to the published literature, we surmise that particulate matter (PM) concentration,
individually, may be less important than components in explaining health effects. PM2. 5 …