Quorum quenching: role in nature and applied developments

C Grandclément, M Tannières, S Moréra… - FEMS microbiology …, 2016 - academic.oup.com
Quorum sensing (QS) refers to the capacity of bacteria to monitor their population density
and regulate gene expression accordingly: the QS-regulated processes deal with …

Tackling antibiotic resistance with compounds of natural origin: A comprehensive review

FJ Álvarez-Martínez, E Barrajón-Catalán, V Micol - Biomedicines, 2020 - mdpi.com
Drug-resistant bacteria pose a serious threat to human health worldwide. Current antibiotics
are losing efficacy and new antimicrobial agents are urgently needed. Living organisms are …

Quorum sensing inhibitors: an overview

VC Kalia - Biotechnology advances, 2013 - Elsevier
Excessive and indiscriminate use of antibiotics to treat bacterial infections has lead to the
emergence of multiple drug resistant strains. Most infectious diseases are caused by …

Exploiting quorum sensing to confuse bacterial pathogens

B LaSarre, MJ Federle - Microbiology and molecular biology …, 2013 - Am Soc Microbiol
Cell-cell communication, or quorum sensing, is a widespread phenomenon in bacteria that
is used to coordinate gene expression among local populations. Its use by bacterial …

The Formation of Biofilms by Pseudomonas aeruginosa: A Review of the Natural and Synthetic Compounds Interfering with Control Mechanisms

T Rasamiravaka, Q Labtani, P Duez… - BioMed research …, 2015 - Wiley Online Library
P. aeruginosa is an opportunistic pathogenic bacterium responsible for both acute and
chronic infections. Beyond its natural resistance to many drugs, its ability to form biofilm, a …

Applying insights from biofilm biology to drug development—can a new approach be developed?

T Bjarnsholt, O Ciofu, S Molin, M Givskov… - Nature reviews Drug …, 2013 - nature.com
Most of the research on bacterial pathogenesis has focused on acute infections, but much
less is known about the pathogenesis of infections caused by bacteria that grow as …

Alternatives to antibiotics for the control of bacterial disease in aquaculture

T Defoirdt, P Sorgeloos, P Bossier - Current opinion in microbiology, 2011 - Elsevier
The wide and frequent use of antibiotics in aquaculture has resulted in the development and
spread of antibiotic resistance. Because of the health risks associated with the use of …

Antimicrobial resistance, respiratory tract infections and role of biofilms in lung infections in cystic fibrosis patients

O Ciofu, T Tolker-Nielsen, PØ Jensen, H Wang… - Advanced drug delivery …, 2015 - Elsevier
Lung infection is the main cause of morbidity and mortality in patients with cystic fibrosis and
is mainly dominated by Pseudomonas aeruginosa. The biofilm mode of growth makes …

Ajoene, a sulfur-rich molecule from garlic, inhibits genes controlled by quorum sensing

TH Jakobsen, M van Gennip, RK Phipps… - Antimicrobial agents …, 2012 - Am Soc Microbiol
In relation to emerging multiresistant bacteria, development of antimicrobials and new
treatment strategies of infections should be expected to become a high-priority research …

Chemical interactions between marine macroalgae and bacteria

F Goecke, A Labes, J Wiese, JF Imhoff - Marine ecology progress series, 2010 - int-res.com
We review research from the last 40 yr on macroalgal–bacterial interactions. Marine
macroalgae have been challenged throughout their evolution by microorganisms and have …