Tight junctions in pulmonary epithelia during lung inflammation

OH Wittekindt - Pflügers Archiv-European Journal of Physiology, 2017 - Springer
Inflammatory lung diseases like asthma bronchiale, chronic obstructive pulmonary disease
and allergic airway inflammation are widespread public diseases that constitute an …

Aquaporins in the lung

OH Wittekindt, P Dietl - Pflügers Archiv-European Journal of Physiology, 2019 - Springer
The lung is the interface between air and blood where the exchange of oxygen and carbon
dioxide occurs. The surface liquid that is directly exposed to the gaseous compartment …

Aquaporins in salivary glands: from basic research to clinical applications

C Delporte, A Bryla, J Perret - International journal of molecular sciences, 2016 - mdpi.com
Salivary glands are involved in saliva secretion that ensures proper oral health. Aquaporins
are expressed in salivary glands and play a major role in saliva secretion. This review will …

Aquaporin: targets for dietary nutrients to regulate intestinal health

H Lv, Y Li, C Xue, N Dong, C Bi… - Journal of Animal …, 2022 - Wiley Online Library
Aquaporins (AQP) are a class of water channel membrane proteins that are widely
expressed in the gut. The biological functions of aquaporins, which regulate the absorption …

[图书][B] Aquaporins in health and disease: new molecular targets for drug discovery

G Soveral, S Nielsen, A Casini - 2018 - books.google.com
Since the discovery of Aquaporin-1 (AQP1) as a water channel, many studies have revealed
the importance of aquaporins in mammalian physiology and pathophysiology as well as …

Aquaporins in salivary glands and pancreas

C Delporte - Biochimica et Biophysica Acta (BBA)-General Subjects, 2014 - Elsevier
Background Salivary glands and pancreas are involved in saliva secretion, pancreatic fluid
secretion and insulin secretion. These functions are essential for proper oral, pancreatic and …

Fluid reabsorption in proximal convoluted tubules of mice with gene deletions of claudin-2 and/or aquaporin1

J Schnermann, Y Huang… - American Journal of …, 2013 - journals.physiology.org
Deletions of claudin-2 (Cldn2) and aquaporin1 (AQP1) reduce proximal fluid reabsorption
(PFR) by about 30% and 50%, respectively. Experiments were done to replicate these …

Water transport in the gastrointestinal tract

JR Thiagarajah, AS Verkman - Physiology of the gastrointestinal tract, 2018 - Elsevier
Large quantities of fluid are transported across epithelial barriers in the gastrointestinal (GI)
tract for secretion of saliva, gastric juice, bile and pancreatic fluid, and for fluid absorption in …

Aquaporins in glandular secretion

G Calamita, C Delporte - Aquaporins, 2023 - Springer
Exocrine and endocrine glands deliver their secretory product, respectively, at the surface of
the target organs or within the bloodstream. The release of their products has been shown to …

Water permeability adjusts resorption in lung epithelia to increased apical surface liquid volumes

H Schmidt, C Michel, P Braubach, M Fauler… - American journal of …, 2017 - atsjournals.org
The apical surface liquid (ASL) layer covers the airways and forms a first line of defense
against pathogens. Maintenance of ASL volume by airway epithelia is essential for …