Tissue engineering often uses synthetic scaffolds to direct cell responses during engineered
tissue development. Since cells reside within specific niches of the extracellular matrix, it is …

Connective tissue is one of the four major types of animal tissue and plays essential roles
throughout the human body. Genetic factors, aging, and trauma all contribute to connective …

Integration between tendon/ligament and bone occurs through a specialized tissue interface
called enthesis. The complex and heterogeneous structure of the enthesis is essential to …

Tendon and ligament (TL) injuries affect millions of people annually. Biopolymers play a
significant role in TL tissue repair, whether the treatment relies on tissue engineering …

Engineered tissue constructs rely on biomaterials as support structures for tissue repair and
regeneration. Among these biomaterials, polyester biomaterials have been widely used for …

The last decade has seen significant developments in cell therapies, based on permanently
differentiated, reprogrammed or engineered stem cells, for tendon injuries and degenerative …

Adult tendon tissue demonstrates a limited regenerative capacity, and the natural repair
process leaves fibrotic scar tissue with inferior mechanical properties. Surgical treatment is …

Recent progress in nanotechnology has stimulated the development of multifunctional
biomaterials for tissue engineering applications. Synergistic interactions between …

Platelet‐Rich Plasma (PRP) has been widely used in orthopaedic surgery and sport
medicine to treat tendon injuries. However, the efficacy of PRP treatment for tendinopathy is …

It is well known that stem cells reside within tissue engineering functional
microenvironments that physically localize them and direct their stem cell fate. Recent efforts …